ch. 11 Flashcards
Caffeine
what are the methylated xanthines
caffeine, theophylline, and theobromine
Is caffeine a stimulant?
Not exactly, as it just blocks adenosine so that our natural promotion of drowsiness is blocked.
where is adenosine found
A lot of it is in the cortex
what is caffeine’s half life
4 hours
how long does it take for caffeine to absorb and get into the brain.
30 mins
what is the peak nervous system stimulation for caffeine?
2 hours
what receptor are most adenosine at?
A1
which drug has the most cardiac stim & Coronary Dilat
theophylline (usually because of too much tea)
what product has caffeine
coffee
what product has theophylline
tea
what product has theobromine
chocolate
how many mg of caffeine is in a cup of coffee
100-150mg
does tea have more caffeine or theophylline?
theophylline (200mg)
what is the diagnosis for too much use of caffeine
“caffeinism (Caffeine Intoxication) as stated in the DSM-3.
How does 500mg effect your metabolic rate?
10% increase in metabolic rate, which can translate to the fetus if you are pregnant.
what is the peak blood absorption of caffeine?
30-60 mins
what is the peak NS absorption of caffeine?
2 hours
what is paraxanthine
caffeine’s psychoactive metabolite.
what is caffeine’s half life
3-5 hours
what is a toxic dose of caffeine?
greater than 10 grams.
what is a theory on how caffeine is related to headache
The fact that caffeine constricts and dilates blood vessels. And the constriction of blood vessels are thought to cause headache.
what amount causes withdrawal of caffeine
about 5 cups a day
what does withdrawal look like with caffiene
headache, nausea, constipation, lethargy
Is coffee really psychologically addicting
the concept of decaf coffee, the taste without the drug, people still drink it regardless.
