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drugs ch.6-12 > ch. 11 > Flashcards

ch. 11 Flashcards

Caffeine

1
Q

what are the methylated xanthines

A

caffeine, theophylline, and theobromine

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2
Q

Is caffeine a stimulant?

A

Not exactly, as it just blocks adenosine so that our natural promotion of drowsiness is blocked.

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3
Q

where is adenosine found

A

A lot of it is in the cortex

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4
Q

what is caffeine’s half life

A

4 hours

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5
Q

how long does it take for caffeine to absorb and get into the brain.

A

30 mins

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6
Q

what is the peak nervous system stimulation for caffeine?

A

2 hours

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7
Q

what receptor are most adenosine at?

A

A1

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8
Q

which drug has the most cardiac stim & Coronary Dilat

A

theophylline (usually because of too much tea)

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9
Q

what product has caffeine

A

coffee

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10
Q

what product has theophylline

A

tea

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11
Q

what product has theobromine

A

chocolate

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12
Q

how many mg of caffeine is in a cup of coffee

A

100-150mg

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13
Q

does tea have more caffeine or theophylline?

A

theophylline (200mg)

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14
Q

what is the diagnosis for too much use of caffeine

A

“caffeinism (Caffeine Intoxication) as stated in the DSM-3.

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15
Q

How does 500mg effect your metabolic rate?

A

10% increase in metabolic rate, which can translate to the fetus if you are pregnant.

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16
Q

what is the peak blood absorption of caffeine?

A

30-60 mins

17
Q

what is the peak NS absorption of caffeine?

A

2 hours

18
Q

what is paraxanthine

A

caffeine’s psychoactive metabolite.

19
Q

what is caffeine’s half life

A

3-5 hours

20
Q

what is a toxic dose of caffeine?

A

greater than 10 grams.

21
Q

what is a theory on how caffeine is related to headache

A

The fact that caffeine constricts and dilates blood vessels. And the constriction of blood vessels are thought to cause headache.

22
Q

what amount causes withdrawal of caffeine

A

about 5 cups a day

23
Q

what does withdrawal look like with caffiene

A

headache, nausea, constipation, lethargy

24
Q

Is coffee really psychologically addicting

A

the concept of decaf coffee, the taste without the drug, people still drink it regardless.

25
Q

Vasodilation

A

the dilation of blood vessels (caffeine can do this as well as constricting blood vessels).

26
Q

does coffee cause cancer?

A

two prestigious cancer research organizations disagree with each other. (there is little evidence for cancer causing properites).

27
Q

can babies in the womb degrade caffeine?

A

it doesn’t have the enzyme to degrade caffeine til after birth

28
Q

Does caffeine cross the placental barrier?

A

yes

29
Q

casement studies

A

over 12 thousand people

30
Q

are panic attacks and caffeine correlated?

A

yes

30
Q

what have we found with caffeine usage during pregnancy

A

caffeine intake was not related to birth defects.

drugs ch.6-12 (7 decks)

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