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Molecular Cell Biology > CH 10: Protein Sorting & Vesicular Trafficking - (Quiz Mode) > Flashcards

CH 10: Protein Sorting & Vesicular Trafficking - (Quiz Mode) Flashcards

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1
Q

The Region of the ER from which Proteins EXIT for the Golgi Apparatus.

  • Autophagosome
  • Signal peptidase
  • Transitional ER
  • Golgi stack
  • Signal patch
A

Transitional ER

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2
Q

A modified Mannose residue that targets Proteins to Lysosomes.

  • Endosome
  • Mannose-6-Phosphate
  • Exocyst
  • Secretory Pathway
  • Phagosome
A

Mannose-6-Phosphate

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3
Q

The Compartments of the Golgi Apparatus w/in which most Metabolic Activities take place.

  • Synaptic Vesicle
  • Golgi Stack
  • SNARE
  • Flippase
  • Mannose-6-Phosphate
A

Golgi Stack

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4
Q

A vesicular compartment involved in the Sorting & Transport to Lysosomes of material taken up by Endocytosis.

  • Clathrin
  • Mannose-6-phosphate
  • Unfolded Protein Response (UPR)
  • Endosome
  • Endoplasmic Reticulum (ER)
A

Endosome

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5
Q

A Particle composed of Proteins & RNA that Binds to Signal Sequences & Targets Polypeptide Chains to the Endoplasmic Reticulum.

  • Mannose-6-Phosphate
  • Signal Recognition Particle (SRP)
  • Clathrin-Coated Vesicle
  • ER-Associated Degradation (ERAD)
  • SRP RNA
A

Signal Recognition Particle (SRP)

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6
Q

A Transmembrane Protein that MEDIATES Fusion of Vesicle(s) & Target Membranes.

  • Microsome
  • Flippase
  • Exocyst
  • SNARE
  • Mannose-6-Phosphate
A

SNARE

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7
Q

The Golgi compartment within which Proteins are Sorted & Packaged to EXIT the Golgi Apparatus.

  • SRP receptor
  • Unfolded Protein Response (UPR)
  • Clathrin-Coated Vesicle
  • Mannose-6-Phosphate
  • trans-Golgi Network
A

trans-Golgi Network

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8
Q

A Recognition Determinant formed by the 3-Dimensional Folding of a Polypeptide Chain.

  • Signal Sequence
  • Phagocytosis
  • Signal Patch
  • SNARE
  • COP-Coated Vesicle
A

Signal Sequence

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9
Q

The Small Cytoplasmic RNA component of SRP.

  • Phagocytosis
  • Endoplasmic Reticulum (ER)
  • SRP RNA
  • Phagosome
  • Signal Sequence
A

SRP RNA

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10
Q

A Protein that CATALYZES the Translocation of Lipids ACROSS the Membrane of the Endoplasmic Reticulum.

  • Flippase
  • Exocyst
  • Mannose-6-Phosphate
  • Autophagosome
  • Vacuole
A

Flippase

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11
Q

A Protein Complex on the Plasma Membrane at which Exocytosis occurs.

  • Phagolysosome
  • Signal Patch
  • Translocon
  • trans-Golgi Network
  • Exocyst
A

Exocyst

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12
Q

The Movement of Secreted Proteins from the Endoplasmic Reticulum to the Golgi Apparatus and then, within Secretory Vesicles, to the Cell Surface.

  • Autophagy
  • trans-Golgi network
  • Secretory Pathway
  • Endosome
  • SRP RNA
A

Secretory Pathway

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13
Q

The UPTAKE of Extracellular Material in Vesicles formed from the Plasma Membrane.

  • Golgi Apparatus
  • Lysosome
  • COPI + COPII
  • Endocytosis
  • Autophagy
A

Endocytosis

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14
Q

A Vacuole containing a Particle taken up by Phagocytosis.

  • Basolateral Domain
  • Autophagosome
  • Exocyst
  • Phagosome
  • Translocon
A

Phagosome

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15
Q

The Surface Region of a POLARIZED Epithelial Cell that is in contact w/ Adjacent cells or the Extracellular Matrix.

  • Clathrin
  • COPI + COPII
  • Basolateral Domain
  • Endocytosis
  • Signal Sequence
A

Basolateral Domain

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16
Q

A Cytoplasmic Organelle containing Enzymes that BREAK DOWN Biological Polymers.

  • Endocytosis
  • COP-coated Vesicle
  • Lysosome
  • Clathrin-Coated Vesicle
  • Basolateral Domain
A

Lysosome

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17
Q

The Region of the Golgi Apparatus @ which Proteins ENTER from the Endoplasmic Reticulum.

  • cis-Golgi network
  • Mannose-6-Phosphate
  • trans-Golgi network
  • Rough ER
  • Basolateral Domain
A

cis - Golgi network

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18
Q

A Membrane-Enclosed Sac that Transports Proteins from the Golgi Apparatus ⟶ Cell Surface.

  • COP-coated Vesicle
  • Clathrin-coated Vesicle
  • Endoplasmic Reticulum (ER)
  • Vacuole
  • Secretory Vesicle
A

Secretory Vesicle

19
Q

A Cellular Stress Response in which an EXCESS of Unfolded Proteins in the Endoplasmic Reticulum LEADS ⟶ General INHIBITION of Protein Synthesis, ⬆︎ (increased) Expression of Chaperones, & ⬆︎ (increased) Proteasome activity.

  • Signal Recognition Particle (SRP)
  • Clathrin-coated Vesicle
  • Unfolded Protein Response (UPR)
  • Phagosome
  • Smooth ER
A

Unfolded Protein Response (UPR)

20
Q

An Enzyme that CATALYZES the Formation & Breakage of Disulfide (S–S) Linkages.

  • Signal Sequence
  • Protein Disulfide Isomerase (PDI)
  • SRP RNA
  • Endoplasmic Reticulum (ER)
  • Phagosome
A

Protein Disulfide Isomerase (PDI)

21
Q

Transport Vesicles Coated w/ COPI or COPII.

  • Golgi apparatus
  • Exocyst
  • Endosome
  • Golgi Stack
  • COP-coated Vesicle
A

COP-coated Vesicle

22
Q

The Region of the Endoplasmic Reticulum covered w/ Ribosomes & involved in Protein Metabolism.

  • Microsome
  • Exocyst
  • Rough ER
  • Unfolded Protein Response (UPR)
  • SRP receptor
A

Rough ER

23
Q

Large Membrane-Enclosed Sac in the Cytoplasm of Eukaryotic Cells. In Plant Cells, these function to store nutrients and waste products, to degrade macromolecules, and to maintain turgor pressure.

  • Signal Patch
  • Transitional ER
  • Vacuole
  • Phagocytosis
  • SRP RNA
A

Vacuole

24
Q

The Membrane Channel through which Polypeptide chains are Transported into the Endoplasmic Reticulum.

  • Lysosomal Storage Disease
  • Translocon
  • Exocyst
  • COP-coated Vesicle
  • Clathrin
A

Translocon

25
Q

The Degradation of Cytoplasmic Proteins & Organelles by their enclosure in Cytoplasmic Vesicles that fuse w/ Lysosomes.

  • trans-Golgi network
  • Protein Disulfide Isomerase (PDI)
  • Microsome
  • Autophagy
  • Phagolysosome
A

Autophagy

26
Q

A Transport Vesicle Coated w/ Clathrin.

  • Autophagy
  • Clathrin-Coated Vesicle
  • Flippase
  • Unfolded Protein Response (UPR)
  • Rough ER
A

Clathrin-coated Vesicle

27
Q

A Glycolipid containing Phosphatidylinositol that ANCHORS Proteins to the External face of the Plasma Membrane.

  • Glycosylphosphatidylinositol (GPI) anchor
  • Translocon
  • ER-Associated Degradation (ERAD)
  • Endocytosis
  • Secretory Pathway
A

Glycosylphosphatidylinositol (GPI) anchor

28
Q

A Cytoplasmic Organelle involved in the Processing & Sorting of Proteins + Lipids. In Plant cells, it is also the site of the synthesis of cell wall polysaccharides.

  • Transitional ER
  • Exocyst
  • Golgi Apparatus
  • ER-Associated Degradation (ERAD)
  • Protein Disulfide Isomerase (PDI)
A

Golgi Apparatus

29
Q

A Vesicle containing Internal Organelles enclosed by fragments of Cytoplasmic membranes that Fuses w/ Lysosomes.

  • Autophagosome
  • Microsome
  • Phagocytosis
  • Rab
  • Smooth ER
A

Autophagosome

30
Q

A Transmembrane Protein that MEDIATES Fusion of Vesicle & Target membranes.

  • Microsome
  • Flippase
  • Exocyst
  • SNARE
  • Mannose-6-Phosphate
A

SNARE

31
Q

A process in which Misfolded Proteins in the ER are IDENTIFIED + RETURNED ⟶ the Cytosol for Degradation by the Ubiquitin-Proteasome System.

  • Exocyst
  • ER-Associated Degradation (ERAD)
  • Endosome
  • trans-Golgi network
  • Endocytosis
A

ER-Associated Degradation (ERAD)

32
Q

An Extensive Network of Membrane-Enclosed Tubules & Sacs involved in Protein Sorting + Processing a/w/a in Lipid Synthesis.

  • COP-coated Vesicle
  • Endocytosis
  • Endoplasmic Reticulum (ER)
  • Rough ER
  • Synaptic Vesicle
A

Endoplasmic Reticulum (ER)

33
Q

The 2 proteins (other than Clathrin) that Coat Transport Vesicles.

  • Glycosylphosphatidylinositol (GPI) Anchor
  • Signal Peptidase
  • Phagolysosome
  • COPI + COPII
  • Mannose-6-Phosphate
A

COPI + COPII

34
Q

The Region of the Endoplasmic Reticulum that is the Major Site of Lipid Synthesis in Eukaryotic Cells.

  • Golgi Apparatus
  • Rab
  • Smooth ER
  • Endocytosis
  • Exocyst
A

Smooth ER

35
Q

A Protein ON the Membrane of the Endoplasmic Reticulum that BINDS the Signal Recognition Particle (SRP).

  • Signal Recognition Particle (SRP)
  • Mannose-6-Phosphate
  • SRP receptor
  • cis-Golgi network
  • Secretory Pathway
A

SRP receptor

36
Q

Family of Small GTP-binding Proteins that play KEY Roles in Vesicular Transport.

  • SRP receptor
  • Golgi Apparatus
  • Rab
  • Autophagy
  • Clathrin-coated Vesicle
A

Rab

37
Q

A Secretory Vesicle that RELEASES Neurotransmitters @ a Synapse.

  • Synaptic Vesicle
  • Phagolysosome
  • COP-coated Vesicle
  • Autophagy
  • Autophagosome
A

Synaptic Vesicle

38
Q

Family of Diseases characterized by the Accumulation of Undegraded material in the Lysosomes of affected individuals.

  • COP-coated Vesicle
  • Endosome
  • Lysosomal Storage Disease
  • Phagocytosis
  • Clathrin-coated Vesicles
A

Lysosomal Storage Disease

39
Q

A Lysosome that has FUSED w/ a Phagosome or Autophagosome.

  • Glycosylphosphatidylinositol (GPI) anchor
  • SRP receptor
  • Phagolysosome
  • Secretory Pathway
  • Rough ER
A

Phagolysosome

40
Q

The UPTAKE of Large Particles, such as Bacteria, by a Cell, sometimes called “Cell Eating.”

  • Autophagosome
  • Phagocytosis
  • Mannose-6-Phosphate
  • Clathrin
  • Golgi stack
A

Phagocytosis

41
Q

An Enzyme that REMOVES the Signal Sequence of a Polypeptide Chain by Proteolysis.

  • Glycosylphosphatidylinositol (GPI) anchor
  • Signal Peptidase
  • Rough ER
  • Golgi Apparatus
  • Signal Sequence
A

Signal Peptidase

42
Q

A Small Vesicle formed from the Endoplasmic Reticulum when Cells are Disrupted.

  • Endocytosis
  • Secretory Vesicle
  • Phagocytosis
  • Microsome
  • ER-Associated Degradation (ERAD)
A

Microsome

43
Q

The Exposed Free Surface of a Polarized Epithelial Cell.

  • Unfolded Protein Response (UPR)
  • Signal Patch
  • Signal Recognition Particle (SRP)
  • Autophagosome
  • Apical Domain
A

Apical Domain

44
Q

HYDROPHOBIC sequence @ the Amino Terminus of a Polypeptide Chain that Targets it for Secretion in Bacteria or incorporation into the Endoplasmic Reticulum in Eukaryotic Cells.

  • Golgi Stack
  • Signal Sequence
  • Signal Peptidase
  • Endosome
  • trans-Golgi network
A

Signal Sequence

Molecular Cell Biology (36 decks)

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