Cervical cancer Flashcards

1
Q

what is the main cause of cervical ca

A

high risk HPV (16 and 18)

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2
Q

What are other RFs for cervcial ca

A
  • Early age intercourse
  • Multiple sexual partners
  • STDs
  • Smoking
  • Previous CIN
  • Multiparity
  • OCP usage
  • Other genital tract neoplasia
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3
Q

Which types of HPV cause warts

A

6 and 11

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4
Q

What cells are most cervcial cancers made up of ?

A

squamous (90%)

adenocarcinoma

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5
Q

What staging is used for cervical ca

A

figo

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6
Q

What are the signs and sx

A

Post coital bleeding is a symptom
Offensive vaginal discharge
IMP or PMB

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7
Q

What are advanced sx

A
−	Heavy vaginal bleeding 
−	Ureteric obstruction
−	Weight loss
−	Bowel disturbance 
−	Pain
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8
Q

Explain staging

A

1 - strictly confined to the cervix
II - extends beyond cervix but not pelvic wall
III - extended into the pelvic sidewall
IV - extended beyond the pelvis

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9
Q

What is the treatment of cervical canceR?

A

LLETZ - early stages
>2cm radical hysterectomy
>stage 2 radio + chemotherapy
surgery - Wertheim’s hysterectomy

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