Cervical cancer Flashcards
1
Q
what is the main cause of cervical ca
A
high risk HPV (16 and 18)
2
Q
What are other RFs for cervcial ca
A
- Early age intercourse
- Multiple sexual partners
- STDs
- Smoking
- Previous CIN
- Multiparity
- OCP usage
- Other genital tract neoplasia
3
Q
Which types of HPV cause warts
A
6 and 11
4
Q
What cells are most cervcial cancers made up of ?
A
squamous (90%)
adenocarcinoma
5
Q
What staging is used for cervical ca
A
figo
6
Q
What are the signs and sx
A
Post coital bleeding is a symptom
Offensive vaginal discharge
IMP or PMB
7
Q
What are advanced sx
A
− Heavy vaginal bleeding − Ureteric obstruction − Weight loss − Bowel disturbance − Pain
8
Q
Explain staging
A
1 - strictly confined to the cervix
II - extends beyond cervix but not pelvic wall
III - extended into the pelvic sidewall
IV - extended beyond the pelvis
9
Q
What is the treatment of cervical canceR?
A
LLETZ - early stages
>2cm radical hysterectomy
>stage 2 radio + chemotherapy
surgery - Wertheim’s hysterectomy