Cerebellum Flashcards
What are the three layers of Gray matter in the cerebellum
- Molecular Layer
- Purkinje Layer
- Granular Layer
What cell types are found in the molecular layer
Basket and Sellate Cells
What cells are found in the granular layer?
granule cells and golgi cells
What is the only excitatory cell type in the Cerebellum?
What NT?
Granule cells
Glutamate
What do the Purkinje cells inhibit?
Cerebellar and Vestibular nuclei (GABA)
What do the stellate cells inhibit?
Purkinje cells
What do the Basket cells inhibit?
Purkinje cells (GABA)
What are the two types of Afferent fibers in the cerebellum?
Mossy Fibers
Climbing Fibers
Where do climbing fibers arise from?
What do they synapse on?
What type of information do they convey?
Inferior Olive (medulla)
Purkinje Fibers
Movement errors information
Where do Mossy fibers arise from?
What do they synapse on?
What kind of information do they convey?
Spinal cord, reticular formation, vestibular system, pontine nuclei
Granulocytes
Somatosensory, arousal, cerebral cortex motor info
What anatomical lobe makes up the Vestibulocerebellum
Flocculonodular lobe
Where does the vestibulocerebellum receive information from?
Where does it send it’s output to?
CN 8
Visual areas
Vestibular apparatus
Vestibular nuclei
Fxn of vestibulocerebellum
Eye movements, muscles of the head (neck and trunk movements)
What anatomical lobes make up the Spinocerebellum?
Vermis and paravermal region
Where does the spinocerebellum receive input from?
Where does it send output to?
spinal interneurons, sensorimotor cortex
Medial UMN and lateral LMN
Fxn of spinocerebellum
Control of ongoing movement
gait and station
What anatomical lobe makes up the cerebrocerebellum?
Lateral hemispheres of cerebellum
Where does the cerebrocerebellum receive input from?
Where does it send output to?
Cerebral cortex, via pontine nuclei
Motor and premotor cortex
Fxn of cerebrocerebellum
Coordination of voluntary movement, planning of movement (mainly UE)
Vestibulocerebellum Big Picture
Afferents
Vestibulocerebellum
Vestibular Nucleus
Spinocerebellum Big Picture
Afferents
Spinocerebellum
Globose and Emboliform Nucleus, and Fastigial Nucleus
Red Nucleus and Thalamus
Cerebrocerebellum Big Picture
Afferents
Cerebrocerebellum
Dentate Nucleus
Red Nucleus and Thalamus
Where does the Fastigial Nucleus receive input from?
Where does it go to?
Spinocerebellum
Vestibulocerebellum
Reticular formation and vestibular nucleus
Of all the afferent fiber pathways entering the cerebellum, which one is the only one made of climbing fibers, and not mossy?
Cortico-olivocerebellar fibers
climbing fibers come from the inferior olive
What tract carries unconscious proprioception from LE?
Posterior spinocerebellar tract
What tract carries unconscious proprioception from UE?
Cuneocerebellar Tract
Where do 1st order neurons of the PSCT tract synapse?
Nucleus dorsalis of Clark
PSCT Tract pathway
LE DRG Gracile Fasiculus [Nucleus dorsalis of Clark] Dorsolateral Funiculus Inferior Cerebellar Peduncle
Where do 1st order neurons of the CCT tract synapse?
Accessory cuneate nucleus
CCT Tract pathway
UE DRG Cuneate Fasiculus Accessory cuneate nucleus Inferior cerebellar nucleus
What is significant about the Anterior Spino-cerebellar tract?
Where do afferent fibers of the anterior spinocerebellar tract run?
Crosses twice- so affects the IL side
Superior cerebellar peduncle
Which peduncle is the major efferent route for the emboliform and dentate nuclei?
Superior cerebellar
Where do afferent fibers of the pontine nuclei run?
Middle cerebellar Peduncle
Where do afferent fibers from the spinal cord run?
Inferior cerebellar peduncle
What are the four deep nuclei of the cerebellum?
Dentate Nucleus
Emboliform
Globose
Fastigial
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