Cerebellum Flashcards

1
Q

What are the three layers of Gray matter in the cerebellum

A
  1. Molecular Layer
  2. Purkinje Layer
  3. Granular Layer
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2
Q

What cell types are found in the molecular layer

A

Basket and Sellate Cells

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3
Q

What cells are found in the granular layer?

A

granule cells and golgi cells

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4
Q

What is the only excitatory cell type in the Cerebellum?

What NT?

A

Granule cells

Glutamate

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5
Q

What do the Purkinje cells inhibit?

A

Cerebellar and Vestibular nuclei (GABA)

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6
Q

What do the stellate cells inhibit?

A

Purkinje cells

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7
Q

What do the Basket cells inhibit?

A

Purkinje cells (GABA)

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8
Q

What are the two types of Afferent fibers in the cerebellum?

A

Mossy Fibers

Climbing Fibers

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9
Q

Where do climbing fibers arise from?

What do they synapse on?

What type of information do they convey?

A

Inferior Olive (medulla)

Purkinje Fibers

Movement errors information

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10
Q

Where do Mossy fibers arise from?

What do they synapse on?

What kind of information do they convey?

A

Spinal cord, reticular formation, vestibular system, pontine nuclei

Granulocytes

Somatosensory, arousal, cerebral cortex motor info

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11
Q

What anatomical lobe makes up the Vestibulocerebellum

A

Flocculonodular lobe

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12
Q

Where does the vestibulocerebellum receive information from?

Where does it send it’s output to?

A

CN 8
Visual areas
Vestibular apparatus

Vestibular nuclei

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13
Q

Fxn of vestibulocerebellum

A

Eye movements, muscles of the head (neck and trunk movements)

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14
Q

What anatomical lobes make up the Spinocerebellum?

A

Vermis and paravermal region

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15
Q

Where does the spinocerebellum receive input from?

Where does it send output to?

A

spinal interneurons, sensorimotor cortex

Medial UMN and lateral LMN

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16
Q

Fxn of spinocerebellum

A

Control of ongoing movement

gait and station

17
Q

What anatomical lobe makes up the cerebrocerebellum?

A

Lateral hemispheres of cerebellum

18
Q

Where does the cerebrocerebellum receive input from?

Where does it send output to?

A

Cerebral cortex, via pontine nuclei

Motor and premotor cortex

19
Q

Fxn of cerebrocerebellum

A

Coordination of voluntary movement, planning of movement (mainly UE)

20
Q

Vestibulocerebellum Big Picture

A

Afferents
Vestibulocerebellum
Vestibular Nucleus

21
Q

Spinocerebellum Big Picture

A

Afferents
Spinocerebellum
Globose and Emboliform Nucleus, and Fastigial Nucleus
Red Nucleus and Thalamus

22
Q

Cerebrocerebellum Big Picture

A

Afferents
Cerebrocerebellum
Dentate Nucleus
Red Nucleus and Thalamus

23
Q

Where does the Fastigial Nucleus receive input from?

Where does it go to?

A

Spinocerebellum
Vestibulocerebellum

Reticular formation and vestibular nucleus

24
Q

Of all the afferent fiber pathways entering the cerebellum, which one is the only one made of climbing fibers, and not mossy?

A

Cortico-olivocerebellar fibers

climbing fibers come from the inferior olive

25
Q

What tract carries unconscious proprioception from LE?

A

Posterior spinocerebellar tract

26
Q

What tract carries unconscious proprioception from UE?

A

Cuneocerebellar Tract

27
Q

Where do 1st order neurons of the PSCT tract synapse?

A

Nucleus dorsalis of Clark

28
Q

PSCT Tract pathway

A
LE 
DRG
Gracile Fasiculus
[Nucleus dorsalis of Clark]
Dorsolateral Funiculus
Inferior Cerebellar Peduncle
29
Q

Where do 1st order neurons of the CCT tract synapse?

A

Accessory cuneate nucleus

30
Q

CCT Tract pathway

A
UE
DRG
Cuneate Fasiculus
Accessory cuneate nucleus
Inferior cerebellar nucleus
31
Q

What is significant about the Anterior Spino-cerebellar tract?

Where do afferent fibers of the anterior spinocerebellar tract run?

A

Crosses twice- so affects the IL side

Superior cerebellar peduncle

32
Q

Which peduncle is the major efferent route for the emboliform and dentate nuclei?

A

Superior cerebellar

33
Q

Where do afferent fibers of the pontine nuclei run?

A

Middle cerebellar Peduncle

34
Q

Where do afferent fibers from the spinal cord run?

A

Inferior cerebellar peduncle

35
Q

What are the four deep nuclei of the cerebellum?

A

Dentate Nucleus
Emboliform
Globose
Fastigial

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