Cerebellum Flashcards

1
Q

What are the three layers of Gray matter in the cerebellum

A
  1. Molecular Layer
  2. Purkinje Layer
  3. Granular Layer
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2
Q

What cell types are found in the molecular layer

A

Basket and Sellate Cells

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3
Q

What cells are found in the granular layer?

A

granule cells and golgi cells

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4
Q

What is the only excitatory cell type in the Cerebellum?

What NT?

A

Granule cells

Glutamate

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5
Q

What do the Purkinje cells inhibit?

A

Cerebellar and Vestibular nuclei (GABA)

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6
Q

What do the stellate cells inhibit?

A

Purkinje cells

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7
Q

What do the Basket cells inhibit?

A

Purkinje cells (GABA)

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8
Q

What are the two types of Afferent fibers in the cerebellum?

A

Mossy Fibers

Climbing Fibers

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9
Q

Where do climbing fibers arise from?

What do they synapse on?

What type of information do they convey?

A

Inferior Olive (medulla)

Purkinje Fibers

Movement errors information

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10
Q

Where do Mossy fibers arise from?

What do they synapse on?

What kind of information do they convey?

A

Spinal cord, reticular formation, vestibular system, pontine nuclei

Granulocytes

Somatosensory, arousal, cerebral cortex motor info

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11
Q

What anatomical lobe makes up the Vestibulocerebellum

A

Flocculonodular lobe

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12
Q

Where does the vestibulocerebellum receive information from?

Where does it send it’s output to?

A

CN 8
Visual areas
Vestibular apparatus

Vestibular nuclei

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13
Q

Fxn of vestibulocerebellum

A

Eye movements, muscles of the head (neck and trunk movements)

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14
Q

What anatomical lobes make up the Spinocerebellum?

A

Vermis and paravermal region

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15
Q

Where does the spinocerebellum receive input from?

Where does it send output to?

A

spinal interneurons, sensorimotor cortex

Medial UMN and lateral LMN

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16
Q

Fxn of spinocerebellum

A

Control of ongoing movement

gait and station

17
Q

What anatomical lobe makes up the cerebrocerebellum?

A

Lateral hemispheres of cerebellum

18
Q

Where does the cerebrocerebellum receive input from?

Where does it send output to?

A

Cerebral cortex, via pontine nuclei

Motor and premotor cortex

19
Q

Fxn of cerebrocerebellum

A

Coordination of voluntary movement, planning of movement (mainly UE)

20
Q

Vestibulocerebellum Big Picture

A

Afferents
Vestibulocerebellum
Vestibular Nucleus

21
Q

Spinocerebellum Big Picture

A

Afferents
Spinocerebellum
Globose and Emboliform Nucleus, and Fastigial Nucleus
Red Nucleus and Thalamus

22
Q

Cerebrocerebellum Big Picture

A

Afferents
Cerebrocerebellum
Dentate Nucleus
Red Nucleus and Thalamus

23
Q

Where does the Fastigial Nucleus receive input from?

Where does it go to?

A

Spinocerebellum
Vestibulocerebellum

Reticular formation and vestibular nucleus

24
Q

Of all the afferent fiber pathways entering the cerebellum, which one is the only one made of climbing fibers, and not mossy?

A

Cortico-olivocerebellar fibers

climbing fibers come from the inferior olive

25
What tract carries unconscious proprioception from LE?
Posterior spinocerebellar tract
26
What tract carries unconscious proprioception from UE?
Cuneocerebellar Tract
27
Where do 1st order neurons of the PSCT tract synapse?
Nucleus dorsalis of Clark
28
PSCT Tract pathway
``` LE DRG Gracile Fasiculus [Nucleus dorsalis of Clark] Dorsolateral Funiculus Inferior Cerebellar Peduncle ```
29
Where do 1st order neurons of the CCT tract synapse?
Accessory cuneate nucleus
30
CCT Tract pathway
``` UE DRG Cuneate Fasiculus Accessory cuneate nucleus Inferior cerebellar nucleus ```
31
What is significant about the Anterior Spino-cerebellar tract? Where do afferent fibers of the anterior spinocerebellar tract run?
Crosses twice- so affects the IL side Superior cerebellar peduncle
32
Which peduncle is the major efferent route for the emboliform and dentate nuclei?
Superior cerebellar
33
Where do afferent fibers of the pontine nuclei run?
Middle cerebellar Peduncle
34
Where do afferent fibers from the spinal cord run?
Inferior cerebellar peduncle
35
What are the four deep nuclei of the cerebellum?
Dentate Nucleus Emboliform Globose Fastigial Dont Eat Greasy Foods