Auditory System (Tracts, Physiology) Flashcards
Steps of Hair cell depolarization
- Sound wave deflects the stereocilia TOWARDS kinocilium
- Causes influx of K+ from endolymph into the cell
- Influx of calcium
- Release of NT (glutamate) via vesicle fusion
Inner hair cells
Primary source of auditory information
Type I afferent
Outer hair cells
Amplifier of auditory information
Type II afferent + efferent fibers
What part of the basilar membrane will respond to low frequency sounds?
What are the characteristics of the basilar membrane here?
Distal end, near helicotrema
Wide and flexible
What part of the basilar membrane will respond to high frequency sounds?
What are the characteristics of the basilar membrane here?
Beginning, near the oval window
Narrow and stiff
What ion channels are responisble for the depolarization of hair cells?
TRPA1 on stereocilia tips
Function of the stria vascularis
maintains the electrochemical properties of endolymph by pumping K+ into endolymph
What protein allows outer hair cells to contract?
Prestin
Where do hair cells receive afferent innervation and efferent innervation from?
Afferent: Spiral ganglia
Efferent: Superior olivary complex
Pathway of Auditory Processing
CNVIII
- Ventral Cochlear Nucleus / Dorsal Cochlear nucleus
- Medial Superior Olivary Complex/ Lateral Superior Olivary Complex
- Inferior Colliculus/ Superior Colliculus
- Brachium of IC
- Medial Geniculate Nucleus (Thalamus)
- Primary Auditory Complex
- Secondary Association Cortex
Fxn of VCN
Nature of sound
Function of DCN
Location of sound
Function of Medial Superior Olivary Complex
Timing of sound
Fxn of Lateral Superior Olivary Complex
Intensity of sound
Fxn of Inferior colliculus
Spatial Map of Sound