Central Nervous System Flashcards
Where is white willow found?
Europe, moist habitats (riverbanks)
What has white willow bark been used for in the past?
chronic pain, fevers, headache, gout
Who provided a detailed account of the use of white willow bark for treating gastrointestinal pain and chronic inflammation?
Leonard Fuchs
What phenolics does white willow contain and what are their properties?
salicin and salicylic acid which have pyretic (fever reducing) and analgesic (pain relieving) properties, and salicylic acid is an anti-inflammatory agent
What are side effects of white willow phenolics?
gastric discomfort and nausea
What company investigated salicylic acid?
Bayer
What was the product called that Bayer semi-synthesized?
acetylsalicylic acid (ASA), patented as Aspirin
What are effects of ASA?
antipyretic, analgesic, and anti-inflammatory; also can reduce the risk of heart attack and stroke, and is an effective treatment for angina
Identifying traits of capsicum pepper
perennial herb, Solanaceae (tomato) family, native to South and Central America
What are the two varieties of pepper?
tabasco type, and habanero type
What causes the hotness of the capsicum pepper?
the proto-alkaloid capsaicin (concentrated where the seeds are)
Where is capsaicin absent?
seeds, leaves, stems, and roots
The burning sensation is caused by capsaicin binding to what receptors?
Vanilloid ion-channel receptors
What does the capsaicin binding result in?
A false signal sent to the brain that mimics the sensation of heat
Why are capsicum peppers popular?
The perception of pain stimulates the release of endorphins which results in a pleasurable sensation