Cellular Components Of The Blood Flashcards
What are thrombocytes
Platelets in exotic species that retain their nucleus
What are white blood cells called
Leucocytes
What are the two divisions of WBCS
Granulocytes
Mononuclear
What are the three types of granulocytes
Neutrophils
Eusinophils
Basophils
Why are granulocytes called granulocytes
They have large numbers of cytoplasmic granules
What colour are the cytoplasmic granules in neutrophils
Neutral (no colour)
What colour are the cytoplasmic granules in eosinophils
Pink
What colour are the cytoplasmic granules in basophils
Dark blue
What are the two types of mononuclear WBCd
Monocytes
Lymphocytes
Where are WBCs peoducted during gestation
Yolk sac
Where are WBCs produced
Bone marrow
Liver/ spleen (if bone marrow is damaged)
What is the half life of neutrophils
6-12hes
What is the half life of platelets
6-8 days
What is the half life of RBCs
110-120 days
What is the stem cell that produces all blood cells called
Hemocytoblast
What does a hemocytoblast divide into
Common myeloid progenitor
Common lymphoid progenitor
What does the common lymphoid progenitor produce
Lymphocytes
What does the common myeloid progenitor cell divide into
Thrombocytes
Platelets
Erythrocytesnast cell
Basophils
Neutrophils
Eosinophils
Monocyte
What is the marrow transit time for granulocytes
1 week
What is the marrow transit time for erythrocytes
3-5days
Where is b lymphocytes produced in birds
Bursa of fabricius
What is endomitosis
Nuclear duplication without cell divisor
What is the process of thromvopoiesis
Endomitosis happens and cell volume increases with each nuclear doviok
Megakaryocyte then forms, and pinches of it can come off from cytoplasm to form platelets
What are the two neutrophil activities
Chemotaxis
Phagocytosis and killing
How does oxygen independent killing of neutrophils work
Occurs at poor blood flow/ abscess
Uses lysozymes
How does oxygen dependent killing of neutrons;hills work
Generates reactive oxygen species that damages bacterial membrane to kill them
How re neutrophils involved in chemotaxis
Neutrophils have selection receptors that interact with selectins on endothelial cells so they express ICAM- 1 and VCAM- 1
Slows down the neutrophils passage
So the neutrophils can escape blood vessel and get to site of inflammation
What species have heterophils
Rabbits
Reptiles
Avian
What are heterophils
Functionally equivalent to neutrophils
Granules stain red
What are the 6 stages of neutrophil development names
Myeloblast
Promuelocyte
Myelocyte
Metamyelocyte
Band neutrophil
Segmented neutrophil
When are eosinohils most common
Allergies
Parasites
Fibrosis
What is the normal range of basophils in blood
0-300
When do you get most basophils
Allergy
Where are mast cells found
Tissues
Where are monocytes found
In blood not tissue
