Cell surface protein (MHC I present on all nucleated cells NOT mature RBCs) Flashcards
1
Q
T cells
A
TCR (binds antigen-MHC complex)
CD3 (associated with TCR for signal transduction)
CD28 (binds B7 on APC)
CXCR4/CCR5 (co-receptors for HIV)
2
Q
Helper T cells
A
CD4, CD40 L
3
Q
Cytotoxic T cells
A
CD8
CXCR4/ CCR5
4
Q
Regulatory T cells
A
CD3/CD4/ CD25/ FOXP3
5
Q
B cells
A
Ig (binds antigen)
CD19, CD20, CD21 (receptor for EBV), CD40
MHC II, B7
6
Q
Macrophages
A
CD14 (receptor for PAMPs, eg, LPS), CD40
CCR5
MHC II, B7 (CD80/86)
Fc and C3b receptors (enhanced phagocytosis)
7
Q
NK cells
A
CD16 (binds Fc of IgG)
CD56 (unique marker for NK)
8
Q
Hematopoietic stem
cells
A
CD34