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Immunology > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

Anti-ACh receptor

A

Myasthenia gravis

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2
Q

Anti-basement membrane

A

Goodpasture

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3
Q

Anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

Anticentromere

A

Limited scleroderma (CREST syndrome)

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5
Q

Anti-desmoglein (anti-desmosome)

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA, anti-Smith

A

SLE

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7
Q

Anti-Jo1, anti SRP, anti-Mi-2

A

Polymyositis, Dermatomyositis

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8
Q

Antimicrosomal/ antithyroglobulin

A

Hashimoto thyroiditis

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9
Q

Antimitochondrial

A

primary biliary cirrhosis

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10
Q

Anti-histone

A

Drug induced lupus

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11
Q

Antihemidesmosome

A

Bullous pemphigoid

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12
Q

Anti-glutamic acid decarboxylase (GAD-65)

A

DM1

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13
Q

Antinuclear (ANA)

A

SLE, nonspecific

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14
Q

Antiparietal cell

A

Pernicious anemia

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15
Q

Antiphospholipase A2 receptor

A

1° membranous nephropathy

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16
Q

Anti-Scl-70 (anti-DNA topoisomerase I)

A

Scleroderma (diffuse)

17
Q

Anti-smooth muscle

A

Autoimmune hepatitis type 1

18
Q

Anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjögren syndrome

19
Q

Anti-TSH receptor

A

Graves disease

20
Q

Anti-U1 RNP (ribonucleoprotein)

A

Mixed connective tissue disease

21
Q

Voltage-gated calcium channel antibodies

A

Lambert-Eaton syndrome

22
Q

IgA anti-endomysial, IgA anti-tissue

transglutaminase

A

Celiac disease

23
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangiitis, eosinophilic
granulomatosis with polyangiitis (Churg-Strauss
syndrome)

24
Q

PR3-ANCA/c-ANCA

A

Granulomatosis with polyangiitis (Wegener)

25
Q 
Rheumatoid factor (IgM antibody that targets
IgG Fc region), anti-CCP (more specific)
A

Rheumatoid arthritis

Immunology (10 decks)

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