Cell Membrane Flashcards
Plasma Membrane model in 1935 by J.R. Danielli and H. Davson, proteins also part included
Sandwich Model
Plasma Membrane model in 1950 by J.D. Robertson
Unit Membrane Model
Plasma Membrane model in 1972 by S.J. Singer and G.L. Nicolson
Fluid Mosaic Model
made of Phospholipids
Plasma Membrane
Red Blood Cells analyzed
Enough for Phospholipid bilayer
Polar heads face out and Nonpolar tails face in
Does not explain why some
nonlipids are permeable
Gorter and Grendel
2 layers of globular proteins with phospholipid inside to make a layer and then join 2 layers together to make a channel for molecules to pass
Sandwich Model
Outer layer of protein with phospholipid bilayer inside, believed all cells same composition, does not explain how some molecules pass through or the use of proteins with nonpolar parts, used transmission electron microscopy
Unit Membrane Model
Phospholipid bilayer with proteins partially or fully imbedded, electron micrographs of freeze-fractured membrane
Fluid Mosaic Model
Structure of the Plasma Membrane
Phospholipid bilayer
Hydrophilic head
Hydrophobic tails
Transmembrane / Intrinsic / Integral
Peripheral / Extrinsic
the plasma membrane is the consistency of olive oil at body temperature, due to unsaturated phospholipids.
Fluid
cells differ in the amount of _________
unsaturated to saturated fatty acid tails
at body temperature it lessens fluidity by restraining the movement of phospholipids, at colder temperatures it adds fluidity by not allowing phospholipids to pack close together
Cholesterol affects fluidity
membrane proteins form a collage that differs on either side of the membrane and from cell to cell (greater than 50 types of proteins), proteins span the membrane with hydrophilic portions facing out and hydrophobic portions facing in. Provides the functions of the membrane
Mosaic
Proteins of the Plasma Membrane Provide 6 Membrane Functions
1) Transport Proteins
2) Receptor Proteins
3) Enzymatic Proteins
4) Cell Recognition Proteins
5) Attachment Proteins
6) Intercellular Junction Proteins
How do materials move into and out of the cell?
Materials must move in and out of the cell through the plasma membrane.
Some materials move between the phospholipids.
Some materials move through the proteins.
three types of passive transport?
Diffusion
Facilitated Diffusion
Osmosis
Molecules can move directly through the phospholipids of the plasma membrane
Diffusion
Materials that pass through the plasma membrane by diffusion
Gases (oxygen, carbon dioxide)
Water molecules (rate slow due to polarity)
Lipids (steroid hormones)
Lipid soluble molecules (hydrocarbons, alcohols, some vitamins)
Small noncharged molecules (NH3)
the net movement of molecules from a high concentration to a low concentration until equally distributed.
Diffusion
Diffusion rate factors
temperature, pressure, state of matter, size of concentration gradient, and surface area of membrane.
substances diffuse through membranes without work by the cell or atp usage
passive transport
Molecules can move through the plasma membrane with the aid of transport proteins
Facilitated Diffusion
is the net movement of molecules from a high concentration to a low concentration with the aid of channel or carrier proteins.
Facilitated Diffusion
How do molecules move through the plasma membrane by facilitated diffusion?
Channel and Carrier proteins
Water Molecules can move directly through the phospholipids of the plasma membrane
Osmosis
is the diffusion of water through a semipermeable membrane. Water molecules bound to solutes cannot pass due to size, only unbound molecules. Free water molecules collide, bump into the membrane, and pass through.
Osmosis
water travels from an area of higher concentration to an area of lower water concentration
Osmosis
Movement _____ when osmotic pressure equals hydrostatic pressure
stops
refers to the total solute concentration of the solution outside the cell.
Tonicity
What are the three types of tonicity
Isotonic
Hypotonic
Hypertonic
prevents bursting of plasma membrane
cell wall