Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Principles of Medicine > Cell integrity > Flashcards

Cell integrity Flashcards

1
Q

What is the inner membrane folds called

A

Cristae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where does oxidative phosphorylation take place

A

Inner membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the reoxidation equations of NADH and FADH2

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Why can NADH generate multiple phosphoanhydride bonds when reoxidised

A

The delta G is much more negative than ATP hydrolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is membrane protein complex 1

A

NADH dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is membrane protein complex 2

A

Succinate dehydrogenase

Succinate-Q reductase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is membrane protein complex 3

A

Q-cytochrome C oxidoreductase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is membrane protein complex 4

A

Cytochrome c oxidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is mobile carrier co-enzyme A

A

Ubiquinone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the second mobile carrier

A

Cytochrome C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What coenzyme bypasses complex 1

A

FADH2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Why are fewer ATP moelcules generated from the reoxidation of FADH2

A

Less protons are pumped into the inter membrane space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does a negative redox potential indicate

A

It has a tendancy to donate electrons

It has more reducing power than hydrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happens to the electrons when they pass down the chain

A

Electrons lose energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which part of ATP synthase is membrane bound

A

F0

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the lollipop head of ATPase called

A

F1

17
Q

What is the cathode and equation of the oxygen electrode

A

Platinum

18
Q

What is the anode and equation of the electrode

A

Silver

19
Q

Graph of the suspension of mitochondria in the oxygen electrode

A
20
Q

What are common failures of oxidative phosphrylation

A

Lack of oxygen

Hypoxia or anoxia

Death can be within a few minute (neurons) or a few hours (muscles)

21
Q

Why are cyanide and azide metabolic poisons

A

They bind with high affinity to the Fe3 form of haem group in cytochrome oxidase complex

22
Q

Why is malonate a metabolic poison

A

Competitive inhibitor to succinate dehydrogenase

Slows down oidation of succinate to fumarate

23
Q

Why is rotenone a metabolic poison

A

Inhibits the transfer of electrons from complex 1 to ubiquinone

24
Q

Why is oligomycin a metabolic poison

A

Inhibits oxidative phosphorylation by binding to the stalk of ATP syntahse and blocking the flow of protons

25
Q

Why is dinitrophenol a metabolic poison

A

It can shuttle protons across the inner mitochondrial membranes

26
Q

Why is DNP used to induce weight loss

A

It transports protons across the mitochondrial membrane which uncouples oxidative phosphorylation

Principles of Medicine (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions