cell injury, cell adaptation Flashcards
Pathophysiology
Systematic study of functional changes in cells/tissues
Pathology
Systematic study of structural alterations in cells/tissues
Disease
Condition in which some functional, biomechanics or genetic abnormality of the body caused a loss of normal health
Aietiology
Cause of disease
Pathogenesis
Mechanisms of development of disease
Morphology
Structural alterations induced in cells and tissues
Clincial maniafestion
Obvious effects of the disease as it’s presents physically
Causes of Cell Injury Hypoxia
Lack of sufficient of o2 to the cell
Ischemia=restriction In blood flow
Chemical Agents
Direct contacts of cells with toxic substance which causes the cell membrane to have increase in permeability
Direct toxicity caused by contact of it chemical with part of the cell membrane and organelles.
Formation of substances that cuss lipids in the cell membrane to be damaged
Nutritional Imbalances
Deficney or over supply of certain nutrients in the body and thus available to the cell
Protein deficiency
Hyperlipidaemia (fat deposits in heart, liver and mm)
Physical agents
Hypo,hyperthermic
Atmospheric pressure
Sunlight
Trauma
Musculoskeletal sprains and strains
Burns
Frostbite
Genetic
changes in the dna of a cell can cause chnage in the structure, function metabloism
more susciptlbe to injury
Infectious Agents
Infectipus mirco-organisms such as HIV virus
meningococcal menigitis
Gangrenous Necrosis
Death of tissue from severe hypoxic injuty, commony in lower leg due to blockage of arterires
Types of Necrosis
Coagulative-occurs in almost all tissues (except brain)
Liquefactive- occurs primarilry in the brain
Casuous- Occurs primarily in the lung doe totuberculosis
Fatty- occurs primarily in the pancreases and abdominal structures
