cell division W5 Flashcards

1
Q

what are three broad reasons that cell division occurs

A

repair tissues
reproduction
replace themselves

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2
Q

what cells undergo MITOSIS

A

somatic cells

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3
Q

what cells undergo meiosis

A

Germ cells

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4
Q

what does ploidy refer to

A

number of sets of chromosomes in a cell

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5
Q

products of mitosis are ….

A

diploid and genetically identical

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6
Q

products of meiosis are …

A

haploid and genetically different

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7
Q

are gametes (sperm and egg cells) haploid or diploid

A

haploid

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8
Q

what is the symbol for haploid

A

n

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9
Q

what is the symbol for diploid

A

2n

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10
Q

phases of the cell cycle

A

G1
S
G2
M

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11
Q

how many chromosomes does a human cell have

A

22+sex chromosome

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12
Q

G1 phase (gap 1) describe (3)

A

cell is functioning normally

major period of cell growth

requires protein synthesis

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13
Q
S phase (synthesis) 
describe (4)
A

Dna is replicated

chromosomes are duplicated

minor period of cell growth

also required protein synthesis

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14
Q
G2 phase (gap 2)
describe (2)
A

rapid cell growth and protein synthesis

preparing for M phase

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15
Q
M phase (mitosis) 
describe (4)
A

cell is dividing

no DNA synthesis (chromosomes already duplicated

no protein synthesis

no gene expression

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16
Q

what disease is caused by uncontrolable cell division

A

cancer

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17
Q

how is the cell cycle regulated

A

through specific proteins called CYCLINS

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18
Q

what are cyclins

A

specific proteins that control the cell cycle

19
Q

what is the consequence of inactivation of cyclins

A

leads to loss of normal control of cell division which can lead to problems such as cancer

20
Q

how are sister chromatids separated during mitosis

A

spindle fibres attacht to kinetochore

21
Q

chromosonal changes are divided into four phases what are they

A

prophase
metaphase
anaphase
telophase

22
Q

describe prophase

A

individual chromosomes become visible as chromatin condenses

23
Q

describe metaphase

A

chromosomes line up in the middle of the cell

24
Q

describe anaphase

A

chromosomes separate

25
Q

describe telophase

A

chromosomes decondense and become chromatin angain

26
Q

what happens when centrioles duplicate

A

the promote assembly of the mitotic spindle microtubules

27
Q

what is cytokinesis

A

the division of the sytoplasm to produce two daughtercells

28
Q

what is the ring between the two halves of the cell during cytokinesis called

A

contractile ring which is in the cleavage furrow

29
Q

where does meiosis occur (2)

to form …

A

germ cells, in testes and ovaries

to form sperm and eggs

30
Q

what are the main phases of meiosis

A

meiosis 1

meiosis 2

31
Q

how many cells are produced from mitosis and are they identical to parent cell

A

2 daughter cells that are identical to parent cell

32
Q

how many cells are produced from meiosis and are they identical to the parent cell, are they identical to each other

A

four daugher cells
all different
and different to parent cell

33
Q

each daughter cell of meiosis is a …..and contains …copy of each chromasome

A

hapolid

one

34
Q

do both emiosis and mitosis have phrophase
metaphase
anaphase
telophase

A

yes

35
Q

what are the phases in meiosis 2

A

similar to mitosis but no ‘S’ phase

G1
G2
M

36
Q

what happens during meiosis 1

A

replicated chromosomes exchange DNA and divide

37
Q

what is homologous recombination

A

exchange of nucleotide sequences between two similar (homologous) DNA molecules

38
Q

meiosis- what is synapsis

A

formation of tetrad

pairing/fusion of homologous chromasomes

39
Q

meiosis - what is chasma

A

point where two homologous non sister chromatids exchange genetic material

40
Q

during which phase does rocombination occur

A

prophase 1

41
Q

what contributes to genetic variation (2)

A

independent assortment

homologous recombination

42
Q

mitosis and cell cycle role in disease(1)

A

errors contribute to cancer progression

43
Q

meiosis roles in disease (3)

A
  • problems with chromosome segregation can contribute to genetic disorders such as down syndrome
  • infertility
  • recombination events associated with genetic disorders