Cell Division and Cellular Organisation Flashcards
Gap phase 1
Cell grows and new organelles and proteins are made
What are the main phases in the cell cycle?
- M Phase (mitosis and cytokinesis)
- G1 (gap phase 1)
- Synthesis
- G2
Gap phase 2
Cell keeps growing and proteins needed for division are made
Synthesis
Cell replicates its DNA, ready to divide by mitosis
G2 checkpoint
The cells check whether all the DNA has been replicated without any damage. If it has then cell can divide by mitosis
G1 checkpoint
The cell checks that the chemicals needed for replication are present and for any damage to the DNA before entering S phase
What is mitosis needed for?
- Growth in multicellular organisms as well as repairing damaged tissues.
- Also a method of asexual reproduction for some plants, animals and fungi
What comes before mitosis in the cell cycle?
-Interphase
Describe what happens in Interphase
- The cell carries out normal functions, but also prepares to divide
- The cell’s DNA is unravelled and replicated, to double it’s genetic content.
- Organelles are also replicated so it has spare ones, ATP content is increased
What are the four stages of mitosis?
- Prophase
- Metaphase
- Anaphase
- Telophase
Describe prophase?
- Chromosomes condense, getting shorter and fatter.
- Centrioles start moving to opposite ends of the cell, forming a network of protein fibres (spindle)
- The nuclear envelope breaks down and chromosomes lie free in the cytoplasm
Centrioles
-Tiny bundles of protein
Describe metaphase?
- The chromosomes (each with 2 chromatids) line up along the middle of the cell and become attached to the spindle by their centromere.
- At the metaphase checkpoint, the cell checks that all the chromosomes are attached to the spindle before mitosis can continue
Describe anaphase?
- The centromeres divide, separating the pairs of sister chromatids.
- The spindle contracts, pulling th chromatids to polar ends of the cell, centromeres first
Describe telophase?
- Chromatids reach polar ends of the cell on the spindle.
- They uncoil and become long and thin again.
- Now called chromosomes again
- A nuclear envelope forms around each group of chromosomes so now there are 2 nuclei