Cell division Flashcards
2 parts of a cell’s life cycle and amount of time spent in each
A: Interphase (90%)
- G1 = growth phase 1
- S-phase = Synthesize a copy of DNA
- G2= growth 2 phase
B: Mitosis & Cytokinesis (10%)
- Prophase
- Metaphase
- Anaphase
- Telophase & cytokinesis
describe what occurs during prophase
- chromatin condenses to chromatids
- centrioles duplicate and move to poles
- spindle fibres form at centrioles and nuclear membrane dissolves
describe what occurs during metaphase
chromosomes (paired chromatids) go to equatorial plate (middle)
describe what occurs during anaphase
centromere breaks, spindle fibers shorten (guide chromatids to opposite poles)
describe what happens during telophase/ cytokinesis
- chromatids reach poles and uncoil, reforming chromatin
- cleavage or cell plate splits cytoplasm & organelles in half
- nuclear membrane reforms
*plants: formation of cell plate before walls. no centrioles
Mitosis produces __ __________ and
meiosis produces ___ ________
- 2 daughters (diploid)
- 4 gemetes (genetically different and haploid)
in (meiosis/ mitosis), crossing over/ synapsis occurs in which phase
meiosis
prophase 1
does the centromere break in meiosis 1 or 2
2
Variation occurs due to : (list 3)`
- crossing over during prophase 1
- random movnt of the chromosomes at anaphase to the poles, produce millions of gene combinations in each gamete
- chance determines which egg and sperm will meet
in fertilization, what do the egg and sperm each contribute
1 sperm (n): contributes DNA only \+ 1 egg (n) contributes DNA and cellular organelles = zygote (2n)
where do mitosis and meiosis each take place?
- mitosis (asexual reproduction): somatic/ body cells
- meiosis (sexual reproduction): in gonads (sex cells)
- spermatogenesis (meiosis) forms __ sperm
- oogenesis (meiosis) forms __ egg and __ polar bodies
- 4
- 1 egg and 3 polar bodies
identical twins
1 fertilized zygote splits into 2
same DNA = identical
fraternal twins
2 fertilizations, same womb
different DNA`
definition of a karyotype
stopping cell cycle in prophase, removing and pairing up maternal and paternal chromosomes to find non-disjuntion disorders (mono/trisomy)
karyotype name of down’s syndrome
trisomy 21
binary fission
dividing (mitosis) into 2 = halves
eg. bacteria and protozoans
budding
outgrowth detach from cell (eg sea anemone)
alteration of generations
sexual stage: produces haploid spores that turn into a plant by meiosis
asexual stage: produces haploid gametes by mitosis that fertilize to become diploid adult plant
parthenogenesis
asexual reproduction: when an unfertilized female egg develops into an adult. The adults may be male or female ( ex daphnia)
Gregory Mendel experiment
the study of heredity (how traits are inherited). experimented with garden peas
gene definition
instructions for producing a particular trait
allele definition
any one of the possible forms of a gene for the same trait
ie yellow or green are alleles for pea pod color
locus definition
specific location of a gene on a chromosome
genotype definition
the genes present (2 alleles make a genotype)
phenotype definition
physical expression of the genotype
eg. tall or short
* environment has big effect on phenotype even though traits are controlled by gemes ( eg rabbit coat color)
test cross
mixing an unknown phenotype with an unknown phenotype
principle of independent assortment
genes on non-homologus chromosomes seperate independently from each other during meiosis
theory of segregation
2n organisms inherit 2 genes for each trait
- these genes are located on pairs of homologous chromosomes that are separated during meiosis
- during meiosis, each gamete (n) only receives one gene per trait
- these genes recombine when the zygote is formed
epistatic gene interaction
genes that interfere with expression of other genes (ie dog coat color)
complementary gene interaction
2 different genes interact to produce a phenotype that neither is able to produce by itself
eg squash shapes
pleiotropic gene interaction
a gene affects many different characteristics
ie sickle cell
the further/ closer (locus) a gene is from a previous cross-over event increases the frequency of the next cross over happening
further apart
only (males/ females) can transmit genetic mutations to their offsprint
females
mendel’s principal of segregation states that alternate forms of a gene separate during
gamete formation
how to differential sex- linked vs autosomal
sex linked= more boys affected than girls
if affected individuals are in every generation of pedigree, it is ______
dominant
____ is the shortest phase in meiosis/ mitosis
metaphase
there is no centromere breakage after meiosis 1, so (haploid/ diploid) after meisosis 1
haploid
examples of sex-linked inheritance to know (3)
red-green colorblindness, hemophilia, baldness
barr-body
tightly condensed, inactive x chromosome in females
eg. calico cats- only female