Cell division Flashcards

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1
Q

When are daughter cells not identical to the parent cell in mitosis?

A

In the rare event of mutation

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2
Q

What period precedes mitosis?

A

Interphase

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3
Q

What happens during interphase?

A

The cell carries out normal functions and the DNA is unravelled and replicated, the organelles grow

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4
Q

What’s the function of the centromere?

A

Joins together the two copies of DNA after replication

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5
Q

What are the stages of mitosis?

A

Prophase, metaphase, anaphase and telophase/cytokinesis

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6
Q

What happens to the chromosomes during prophase?

A

Become visible, initially as long thin threads, they are drawn to the equator of the cell by the spindle fibres attached to the centromere

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7
Q

What are centrioles?

A

Two cylindrical organelles in animal cells, that move to the poles of the cell

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8
Q

What do the centrioles do during prophase?

A

Spindle fibres develop and span the cell from poles, collectively this is called the spindle apparatus

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9
Q

What happens to the nucleus during prophase?

A

Nucleolus disappears and nuclear envelope break down, leaving the chromosomes free in the cytoplasm

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10
Q

When are chromosomes made to be seen as two chromatids?

A

Metaphase

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11
Q

What happens during metaphase?

A

The chromosomes are pulled across the spindle apparatus towards the equator of the cell

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12
Q

What happens during anaphase?

A

Centromeres divide into two and the spindle fibres pull the individual chromatids to poles where they are now considered chromosomes

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13
Q

Where is the energy for anaphase provided from?

A

Mitochondria

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14
Q

What happens if cells are treated with chemicals that destroy the spindle fibres?

A

The chromosomes remain at the equator, unable to reach the poles

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15
Q

What happens to the chromosomes during telophase?

A

The chromosomes reach their respective poles and become longer and thinner, finally disappearing altogether, leaving widely spread chromatin

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16
Q

What happens to the spindle fibres and nucleus during telophase?

A

Spindle fibres disintegrate and nucleolus and nuclear envelope reform

17
Q

What is cytokinesis?

A

The division of the cytoplasm

18
Q

How do prokaryotic cells divide?

A

Binary fission

19
Q

What happens to DNA during binary fission?

A

Circular DNA molecule replicates and both copies attach to the cell membrane, plasmids also replicate

20
Q

What happens to the cell membrane of binary fission?

A

Cell membrane begins to grow and pinch inwards, dividing into two

21
Q

What are the daughter cells of binary fission?

A

Identical circular DNA with variable number of copies of the plasmids

22
Q

How do viruses replicate?

A

Attaching to the host cell with attachment proteins on the surface and injecting nucleic acid with info to replicate it

23
Q

What do host cells produce to replicate the virus?

A

Viral components, nucleic acids, enzymes and structural proteins

24
Q

What are the three stages of the cell cycle?

A

Interphase, nuclear division and cytokinesis

25
Q

What stage occupies most of the cell cycle?

A

Interphase- 90%

26
Q

What is the typical cell cycle length in a mammalian cell?

A

24 hours

27
Q

How many cancer diseases are there?

A

Around 200

28
Q

What causes cancer?

A

Damage to the genes that regulate mitosis and the cell cycle, leading to exponential growth of abnormal cells causing expanding tumours

29
Q

Where are tumours most commonly found?

A

Lungs, prostate gland, breast and ovaries, large intestine, stomach, oesophagus and pancreas

30
Q

How does chemotherapy usually disrupt the cell cycle?

A

Preventing DNA replication, interfering with spindle formation