Cell Cycle Flashcards
Sequence of phases in the life cycle of the cell
CELL CYCLE
Longest event in the cycle
(G1, S, and G2 phases)
Interphase
Cell GROWS and makes a new copy of DNA
Interphase
packs enough nutrients for the new daughter cells
Interphase
(Eukaryotic cell spends most of its life in the stage called)
The cell grows larger
Duplicates the organelles
Makes the molecular building blocks needed
for the succeeding steps
Creates nucleiotides
Intense metabolic activities
First Gap (G1)
DNA replication and duplication of centrosomes occur
Synthesis Phase
Cell grows continuously
Fills up the loss of energy during the S phase
Making more proteins
Continuously duplicating the organelles
Completing the preparations for the mitotic phase.
Second Gap (G2)
Duplication division
Distribution of chromosomes into 2 daughter nuclei
M Phase
Division of the cytoplasm producing 2 identically daughter cells
Cytokinesis
Nuclear division in eukaryotes occurs by
Mitosis
When cells are not dividing, their DNA exists as
Chromatin
They are reproductive cells
Gametes
When homologous chromosomes/sister chromatids don’t separate during meiosis
Nondisjunction
Resting place/Non-diving state
G0 Phase
Why do cells enter G0 phase?
Unfavorable environmental conditions (not enough nutrients & energy)
Waiting for signals to enter G1
Permanent state for some cells like nerve & cardiac muscle cells
How long does a whole cell cycle take?
24 hours
How long G1 Phase take?
5 to 6 hours
How long S Phase take?
10 to 12 hours
How long G2 Phase take?
4 to 6 hours
How long does mitosis phase take?
greater than 1 hour
Control System
Cyclin
CDK Complexes
p53
Two types of regulatory proteins are involved in cell cycle control
cyclins and cyclin-dependent kinases(Cdks)
is a cyclin-Cdk complex that triggers a cell’s passage past the G2 checkpoint into the M phase
MPF (maturation-promoting factor)
Undergo a constant cycle of synthesis
Cyclin