Cell cycle Flashcards

1
Q

What are the stages of interphase?

A

G1
S
G2

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2
Q

What occurs in G1 phase?

A

Cell growth

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3
Q

What occurs in S phase?

A

DNA replication

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4
Q

What occurs in G2 phase?

A

cells duplicate organelles

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5
Q

What are the checkpoints of the cell cycle?

A

G1 checkpoint before S phase
G2 checkpoint before M phase

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6
Q

What happens to a cell if DNA damage is recognised?

A

apoptosis or enters G0 phase - arrests

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7
Q

What is the point of the checkpoints?

A

check for DNA damage

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8
Q

What does mitotic phase involve?

A

mitosis and cytokinesis

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9
Q

What are the phases of mitosis?

A

prophase, metaphase, anaphase and telophase

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10
Q

What happens at prophase?

A

nuclear membrane disappears, chromosomes condense and become visible

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11
Q

What happens at metaphase?

A

chromosomes align at metaphase plate and attach to spindle fibres at kinetochore

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12
Q

What happens at anaphase?

A

spindle fibres contract, pull sister chromatids apart to opposite poles of cell

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13
Q

What happens at telophase?

A

nuclear membrane reforms around new chromosomes, cytoplasm divides

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14
Q

What happens in cytokinesis?

A

cleavage furrow develops around equator region, cells separate - 2 daughter cells formed

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15
Q

What is non-disjunction?

A

when chromosomes fail to migrate properly in anaphase, one cell receives more chromosomes, one deficient

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16
Q

What is isochromosome?

A

chromosomes unequal lengths due to centromere splitting transversely