Cell Adaptation Flashcards

1
Q

what is hypertrophy?

A

increased size of cells

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2
Q

where is hypertrophy most common?

A

heart
skeletal muscle
organ/tissues

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3
Q

what is hyperplasia?

A

increased number of cells

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4
Q

why does hyperplasia occur?

A

hormonal
compensatory

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5
Q

is pathologic hyperplasia fulfilling a functional need?

A

no

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6
Q

what is metaplasia?

A

replacement of a cell type by another of the same germline
change from one differentiated cell to another cell type

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7
Q

what would squamous cell in the wrong place in the respiratory tract indicate?

A

squamous metaplasia

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8
Q

what is dysplasia?

A

abnormal pattern of tissue growth, disorderly arrangement of cells within epithelium

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9
Q

is dysplasia often associated with hyperplasia and/or metaplasia?

A

yes

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10
Q

what is atrophy?

A

decreased size of cells

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11
Q

what is hypoplasia?

A

when an organ fails to achieve its full size

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12
Q

is hypoplasia congenital?

A

yes

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13
Q

true/false: atrophy can be both a cause and/or a result of a disease process (pathologic)

A

true

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14
Q

is increased functional demand associated with hypertrophy?

A

yes

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15
Q

what is pathologic hypertrophy?

A

limit to which hypertrophy can compensate

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16
Q

what are two examples of hypertrophy?

A

skeletal muscle: increases mitochondria and contractile proteins
arterial smooth muscle: pulmonary hypertension

17
Q

what is pathologic hypertrophy?

A

a limit to which hypertrophy can compensate
energy metabolism of hypertrophied cells cannot keep pase with increased functional demand

18
Q

what are the two types of physiologic hyperplasia?

A

hormonal
compensatory

19
Q

is atrophy reversible?

A

yes

20
Q

are cell adaptations reversible?

A

often yes, but may lead to organ failure or cancer