CC Progress Exam Flashcards
Levels may become elevated as one changes position from supine to upright:
A. ACTH and cortisol
B. Aldosterone and insulin
C. Growth hormone and ACP
D. Albumin and calcium
D. Albumin and calcium
Peaks early to late morning; decreases up to 30% during the day:
A. Growth hormone
B. Acid phosphatase
C. Calcium
D. Iron
D. Iron
Methods used to measure the concentrations of large particles such as antigen–antibody complexes, prealbumin, and other serum proteins:
A. Nephelometry
B. Turbidimetry
C. Nephelometry and turbidimetry
D. Nephelometry, turbidimetry and absorption spectroscopy
C. Nephelometry and turbidimetry
The measurement of voltage between two electrodes in a solution forms the basis for a variety of procedures for measuring analyte concentration:
A. Potentiometry
B. Coulometry
C. Amperometry
D. Voltammetry
A. Potentiometry
It is based on fragmentation and ionization of molecules using a suitable source of energy:
A. Conductance
B. Impedance
C. Chromatography
D. Mass spectrometry
D. Mass spectrometry
Generally it is used to detect gamma radiation:
A. Crystal scintillation counter
B. Liquid scintillation counter
C. Crystal and liquid scintillation counter
D. None of these
A. Crystal scintillation counter
A technique for determining the structure of organic compounds; it is nondestructive, although it does require a larger sample volume:
A. Mass spectroscopy
B. Nuclear magnetic resonanance
C. Capillary electrophoresis
D. Mass spectroscopy and nuclear magnetic resonance
B. Nuclear magnetic resonanance
Common causes of hypernatremia, EXCEPT:
A. Dehydration
B. Diabetes insipidus
C. Cushing’s disease or syndrome
D. Syndrome of inappropriate ADH (SIADH) secretion
D. Syndrome of inappropriate ADH (SIADH) secretion
In all forms of hyponatremia, the chloride ion concentration is also generally ____ because chloride is the chief counterion for sodium.
A. High
B. Low
C. Variable
D. Cannot be determined
B. Low
Low anion gaps:
A. Uremia/renal failure
B. Uremia/renal failure, ketoacidosis and salicylate poisoning
C. Hypoalbuminemia and severe hypercalcemia
D. Hypoalbuminemia, hypercalcemia and multiple myeloma
D. Hypoalbuminemia, hypercalcemia and multiple myeloma
In panhepatic cirrhosis there is destruction of _____ of liver tissue.
A. Less than 50%
B. More than 50%
C. Less than 80%
D. More than 80%
D. More than 80%
A definitive test for congestive heart failure and appears to be an excellent marker for early heart failure:
A. CK and AST
B. CK, AST and LD
C. CK-MB and troponin
D. B-type natriuretic peptide
D. B-type natriuretic peptide
The main waste product of nitrogen-containing chemicals in the body:
A. Ammonia
B. Creatinine
C. Urea
D. Uric acid
C. Urea
This protein appears in the urine when reabsorption is incomplete because of the proximal tubular damage as in acute kidney injury:
A. Urea
B. Creatinine
C. Alpha2-macroglobulin
D. Beta2-microglobulin
D. Beta2-microglobulin
It is characterized by a sudden onset of hematuria and proteinuria and a decrease in glomerular filtration rate characterized by a rise in plasma creatinine and a fall in creatinine clearance compared with reference ranges:
A. Acute glomerular nephritis
B. Chronic glomerular nephritis
C. Diabetic nephropathy
D. Systemic lupus erythematosus
A. Acute glomerular nephritis
Chronic glomerular nephritis
A. Slower developing disease and may be idiopathic
B. Characterized by gradual uremia
C. Loss of functioning nephrons
D. Slower developing disease and may be idiopathic, and is characterized by gradual uremia and loss of functioning nephrons
D. Slower developing disease and may be idiopathic, and is characterized by gradual uremia and loss of functioning nephrons
A substance that increases the concentration of hydrogen ion (H+) when dissolved in water:
A. Acid
B. Base
C. Neutral
D. Buffer
A. Acid
A substance that increases the concentration of hydroxyl ion (OH–) when dissolved in water:
A. Acid
B. Base
C. Neutral
D. Buffer
B. Base
The combination of a weak acid or weak base and its salt, is a system that resists changes in pH:
A. Acid
B. Base
C. Neutral
D. Buffer
D. Buffer
The role of the lungs and kidneys in maintaining pH is depicted with the Henderson-Hasselbalch equation. The numerator denotes:
A. Kidney function
B. Lung function
C. Either kidney or lung function
D. None of these
A. Kidney function
The role of the lungs and kidneys in maintaining pH is depicted with the Henderson-Hasselbalch equation. The denominator denotes:
A. Kidney function
B. Lung function
C. Either kidney or lung function
D. None of these
B. Lung function
Lung diseases such as chronic obstructive lung disease, advanced interstitial lung disease and acute asthma are causes of:
A. Respiratory acidosis
B. Respiratory alkalosis
C. Metabolic acidosis
D. Metabolic alkalosis
A. Respiratory acidosis
The fifth most common element and is the most prevalent cation in the human body:
A. Calcium
B. Magnesium
C. Potassium
D. Sodium
A. Calcium
The fourth most abundant cation in the body and the second most prevalent intracellular cation:
A. Calcium
B. Magnesium
C. Potassium
D. Sodium
B. Magnesium
There usually is an autoimmune destruction of insulin-producing beta cells in the islets of the pancreas, causing an absolute deficiency in insulin production.
A. Type 1 diabetes mellitus
B. Type 2 diabetes mellitus
C. Type 1 and 2 diabetes
D. Gestational diabetes
A. Type 1 diabetes mellitus
Most widely used to assess short-term(3- to 6-week) glycemic control:
A. Plasma glucose levels
B. Glycosylated hemoglobin
C. Fructosamine
D. Ketone testing
C. Fructosamine
It plays a key role in role in reverse cholesterol transport, the process by which excess cholesterol is returned from tissues to the liver, where it is reused or excreted in bile:
A. Chylomicrons
B. VLDL
C. LDL
D. HDL
D. HDL
An abnormal lipoprotein found in patients with obstructive biliary disease and in patients with familial lecithin/cholesterol acyltransferase (LCAT) deficiency:
A. Intermediate-density lipoproteins
B. Lipoprotein (a)
C. LpX lipoprotein
D. LDL
C. LpX lipoprotein
Lipoprotein(s) have a density of less than 1.006 kg/L (density measurement):
A. HDL
B. LDL
C. LDL and HDL
D. Chylomicrons and VLDL
D. Chylomicrons and VLDL
A rare autosomal recessive disorder characterized by complete absence of HDL:
A. LCAT deficiency
B. Hepatic lipase deficiency
C. Familial hypoalphalipoproteinemia
D. Tangier disease
D. Tangier disease
It plays a significant role in the metabolism of vitamin A by complexing with the retinol-binding protein (RBP), which, in turn, complexes with vitamin A to transport it through the body:
A. Albumin
B. Alpha1-antitrypsin
C. Prealbumin
D. Transferrin
C. Prealbumin
This protein, also known as orosomucoid, has a very high carbohydrate content, which minimizes its visualization by standard protein stains:
A. Gc-globulin
B. Hemopexin
C. C-reactive protein
D. Alpha1-acid glycoprotein
D. Alpha1-acid glycoprotein
A striking elevation of transferrin in the β-region sometimes occurs in patients suffering from:
A. Acute inflammation
B. Chronic inflammation
C. Nephrotic syndrome
D. Iron deficiency anemia
D. Iron deficiency anemia
Enzymes _____ the activation energies of the chemical reactions that they catalyze, so as to cause greatly enhanced rates of reaction.
A. Elevate
B. Lower
C. Affect variably
D. Produces no effect
B. Lower
Different forms of enzymes that catalyze the same reaction:
A. Activators
B. Coenzymes
C. Isoenzymes
D. Substrates
C. Isoenzymes
A nonprotein molecule necessary for enzyme activity:
A. Activators
B. Apoenzymes
C. Coenzymes
D. Cofactors
D. Cofactors
Stated as E + S = ES = E + P
A. Catalytic mechanism
B. Henderson-Hasselbalch equation
C. Lineweaver-Burk plot
D. Combination reaction
A. Catalytic mechanism
In liver or skeletal muscle disease, which LD isozymes become elevated predominantly in serum?
A. LD1 and LD2
B. LD2 and LD3
C. LD3 and LD4
D. LD4 and LD5
D. LD4 and LD5
This probably represents alcohol dehydrogenase:
A. LD1
B. LD3
C. LD5
D. LD6
D. LD6
(3) Causes of elevated serum levels of unconjugated bilirubin:
A. Dubin-Johnson syndrome
B. Biliary obstruction
C. Hemolysis
D. Gilbert’s syndrome
E. Crigler-Najjar syndrome
C. Hemolysis
D. Gilbert’s syndrome
E. Crigler-Najjar syndrome
(2) Causes of elevated serum levels of conjugated bilirubin:
A. Dubin-Johnson syndrome
B. Biliary obstruction
C. Hemolysis
D. Gilbert’s syndrome
E. Crigler-Najjar syndrome
A. Dubin-Johnson syndrome
B. Biliary obstruction
Given the common practice of dismissing mother and newborn baby within 48 hours of the mother’s admission, it is likely that the neonate’s thyroxine levels may:
A. Increase above the normal reference ranges due to starvation
B. Increase above the normal reference ranges due to hyperthyroidism
C. Fall below normal references ranges due to congenital hypothyroidism
D. Fall below normal references ranges due to inadequate protein feeding
D. Fall below normal references ranges due to inadequate protein feeding
It usually associated with a single, short-term exposure to a substance, the dose of which is sufficient to cause immediate toxic effects:
A. Acute toxicity
B. Chronic toxicity
C. Either acute or chronic toxicity
D. None of these
A. Acute toxicity
It is usually associated with repeated frequent exposure for extended periods for greater than 3 months and possibly years, at doses that are insufficient to cause an immediate response:
A. Acute toxicity
B. Chronic toxicity
C. Acute and chronic toxicity
D. None of these
B. Chronic toxicity
This drug is traded on the streets under the name of angel dust or angel hair:
A. Cocaine
B. Amphetamine
C. Phencyclidine
D. Benzodiazepine
C. Phencyclidine
Panic reactions—a bad trip—are the most common adverse reactions.
A. Methaqualone
B. Marijuana
C. Phencyclidine
D. Lysergic acid diethylamide
D. Lysergic acid diethylamide