Case 21- SAP and Physiology Flashcards

1
Q

How ones own prejudice can impact clinical decision making?

A

Decreased doctor patient relationship
Missed diagnosis
Lack of empathy towards patient
Incomplete diagnosis

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2
Q

Attribution

A

Refers to the fact that humans are motivated to assign causes to their actions and behaviours, as either being internal or external

E.g. is someone angry because something bad happened or because they have a bad temper - it is up to us to attribute an answer to this

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3
Q

Interpersonal attribution

A

The tendency for individuals to tell a story in a way that characterises them in the best light possible

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4
Q

Predictive attribution

A

We assign things in ways that allow us to make future predictions

E.g. if your car is broken in to you attribute it to the fact you parked in a particular place so wont park there again

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5
Q

Explanatory attribution

A

The tendency for us to make attributions that help us make sense of the world around us (i.e. explaining something as God’s plan)

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6
Q

Origins and nature of stereotyping

A

Stereotyping is creating an oversimplified image of a particular group of people by making one rule and assuming everyone else in the group fits under this rule

Stigmas are labels that form these stereotypes

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7
Q

Origins and nature of prejudice

A

Prejudice is having a preconceived opinion that is not based on reason or actual experience

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8
Q

Attribution value model of prejudice

A

People are prejudiced against groups that they feel they have some negative attribute for which they are held responsible for

E.g. thinking overweight people are lazy

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9
Q

Origins and nature of discrimination

A

Discrimination is unjustifiable negative behaviours and treatment towards a group and its members which leads to adverse consequences

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10
Q

Pathology- conjunctiva

A

Conjunctiva- lines the inside of the eyelids and reflects to cover the sclera, attaching at the limbus (where the sclera and cornea join)

Pathology: Conjunctivitis

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11
Q

Pathology- Subconjunctival area

A

Subconjunctival region- under the conjunctiva

Pathology: Subconjunctival haemorrhage

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12
Q

Pathology- Sclera and cornea

A

Outer fibrous layer of the eyeball-sclera and cornea

Pathology: Episcleritis (outer/superficial layer of sclera), Scleritis (deeper layers), Corneal ulcer/abrasion.

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13
Q

Pathology- Anterior chamber

A

Anterior chamber-chamber between the iris and cornea

Pathology: Glaucoma-closed angle

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14
Q

Pathology- Uvea/middle layer of the eyeball

A

Uvea/Middle layer of the eyeball-choroid, ciliary body and process, iris
Pathology: Uveitis

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15
Q

Painful red eye- Bacterial keratitis

A

Inflammation of the cornea.

Anything that disrupts the epithelial surface of the cornea can predispose it to infection e.g. trauma or contact lens wear.

Features:
Pain
Blurred vision
Photophobia
Gritty sensation
Forms a round lesion on fluorescein staining
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16
Q

Bacterial keratitis- Management

A

Diagnosis- Use fluorescein eye drops to visualise infective keratitis. It stains any defects in the corneal epithelium.
Management- Refer the patient to the emergency eye service for same-day assessment due to the risk of visual loss. Do not continue to wear the contact lenses and take the lenses to the hospital to be swabbed.

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17
Q

Painful red eye- viral keratitis

A

History of cold sores
Dendritic/branching ulceration
Reduced corneal sensation
Management- Refer the patient to the emergency eye service for same-day assessment due to the risk of visual loss. Do not continue to wear the contact lenses and take the lenses to the hospital to be swabbed.

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18
Q

Painful red eye- Anterior scleritis

A

Uncommon, Associated with autoimmune disease, infections and trauma.

Features:
Severe boring pain with globe tenderness.
Worse at night waking the patient from sleep.
Reduction in vision.
Photophobia
Sectoral or diffuse redness
Sclera may appear blue/grey- the sclera becomes more translucent

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19
Q

Anterior scleritis- management

A

Refer patients with severe eye pain and a significant reduction in vision immediately for same-day assessment

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20
Q

Painful red eye- acute angle closure glaucoma

A

The iris pushes forward against the trabecular meshwork preventing the drainage of aqueous humour.

Features:
Pain
Blurred vision
Nausea and vomiting
Haloes 
Mid dilated fixed pupil
Cloudy cornea
Conjunctival injection
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21
Q

Acute angle closure glaucoma- management

A

Refer the patient to the emergency eye service for same-day assessment due to the risk of visual loss
Occurs in individuals with risk factors- narrow anterior chamber, long sighted, cataracts

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22
Q

Painful red eye- Anterior uveitis

A

Inflammation of the iris and ciliary body

Causes= Idiopathic, Trauma, infection, autoimmune conditions-HLA-B27

Features:
Photophobia-due to the movement of an irritated iris
Pain
Blurred vision-due to debris in the anterior chamber
Headache
Watery eye
Peri-limbal hyperaemia
Abnormal pupil shape
Hypopyon- inflammatory cells in the anterior chamber

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23
Q

Anterior uveitis- management

A

Refer patients with severe eye pain and a significant reduction in vision immediately for same-day assessment

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24
Q

Painful red eye- Endophthalmitis

A

Infection of the aqueous and vitreous humour.

Post surgery
Post trauma
Endogenous – associated with severe systemic infection or intravenous drug use

Features:
Blurred vision
Red eye
Pain
Photophobia
Swollen lid
Hypopyon- inflammatory cells in the anterior chamber 
Hazy appearance
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25
Q

Endophthalmitis- management

A

Refer patients with severe eye pain and a significant reduction in vision immediately for same-day assessment. Patients with endogenous endophthalmitis can become very unwell

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26
Q

Flow chart- Episcleritis

A

Pain- mild/none

Redness- Focal

27
Q

Flow chart- Subconjunctival haemorrhage

A

Pain- mild/none
Redness- Diffuse
Discharge- None

28
Q

Flow chart- Chlamydial conjunctivitis/Bacterial conjunctivitis

A

Pain- mild/none
Redness- diffuse
Discharge- mucopurulent

29
Q

Flow chart- Allergic conjunctivitis

A

Pain- mild/none
Redness- diffuse
Discharge- watery, itchy

30
Q

Flow chart- viral conjunctivitis

A

Pain- mild/none
Redness- diffuse
Discharge- watery, no itch

31
Q

Flow chart- viral keratitis

A

Pain- mod/severe

Fluorescein stain uptake- yes, branching

32
Q

Flow chart- bacterial keratitis

A

Pain- mod/severe

Fluorescein stain uptake- yes, round

33
Q

Flow chart- corneal abrasion

A

Pain- mod/severe

Fluorsecein stain uptake- yes, neither branching or round

34
Q

Flow chart- Scleritis

A

Pain- mod/severe
Fluoescein stain uptake- no
Pupil- pupil small or normal, deep pain

35
Q

Flow chart- anterior uveitis

A

Pain-mod/severe
Fluorscein stain uptake- no
Pupil small or normal
Photophobia

36
Q

Flow chart- acute angle glaucoma

A

Pain- Mod/severe
Fluorsecein stain uptake- no
Pupil enlarged and fixed

37
Q

Visual loss- Acute painful

A
Migraine
Keratitis
Anterior uveitis
Optic neuritis
Endophthalamitis
Orbital cellulitis
Acute angle closure glaucoma
38
Q

Visual loss- acute painless

A
Retinal detachment
Acute ischaemic optic neuropathy
Central retinal vein occlusion
Wet ARMD
Central retinal artery occlusion
Vitrous haemorrhage
Stroke
39
Q

Visual loss- Chronic painless

A
Cataract
Tumour
Dry ARMD
Open angle glaucoma
Diabetic retinopathy
40
Q

Acute painful visual loss- Optic neuritis causes

A

Inflammation of the optic nerve

Cause:
Demyelination-may be the first presentation of multiple sclerosis
Inflammation
Infection
Ischaemia
41
Q

Acute painful visual loss- Optic neuritis Features

A
Visual loss
Relative afferent pupillary defect
Pain on eye movement
Reduced acuity
Impaired colour vision
Visual field loss
Mild disc swelling or normal disc
42
Q

Visual loss acute painful- Migraine

A
Cause: Many triggers specific to an individual
Features:
Preceding aura
Headache
Nausea
Photophobia
Phonophobia
Scintillating scotoma – zig-zag lines
43
Q

Visual loss acute painful- Orbital cellulitis (Causes, features)

A

Cause: Cellulitis (bacterial infection) in this region is divided into-
Pre-septal- anterior to the orbital septum
Orbital- posterior to the orbital septum

Features:
Emergency-risk of intracranial infection, sepsis and visual loss.
Double vision, pain on eye movements, reduced acuity.

44
Q

Orbital cellulitis- Treatment

A

1) Emergency referral to ophthalmology

2) IV antibiotics

45
Q

Acute painless visual loss- Retinal artery occlusion (Risk factors, symptoms)

A

Risk factors:
Embolism
Vasculitis (giant cell arteritis)
Clotting disorders

Symptoms:
Varied degrees of visual loss-dependent on the point of occlusion
Causes ischaemia distal to the occlusion

46
Q

Retinal artery occlusion- On examination / Management

A
O/E:
Pale retina due to nerve fibre ischaemia
Cherry red spot at macula-due to visible choroid in this region
Visual field loss
Loss of visual acuity

Management:
If presenting within 12 hours of vision loss-ocular massage, rebreathing into a paper bag, acetazolamide.
Management of cardiovascular risk factors-high risk of stroke

47
Q

Visual loss- acute painless= Retinal vein occlusion (Risk factors/cause)

A
Risk factors:
Age
Smoking
Hypertension
Diabetes
Combined oral contraceptive pill

Cause:
Thrombus formation
Compression by external structures

48
Q

Features of Retinal vein occlusion

A

Sudden loss of vision-visual acuity is dependent on the level of retinal ischaemia
“Stormy sunset” or “blood-and-thunder” appearance:
Retinal haemorrhages
Cotton wool spots
Tortuous retinal veins-due to the swelling of the retina
Macula oedema

49
Q

Acute painless visual loss- Anterior ischaemic optic neuropathy

A

Features: Vision loss with disc swelling and hyperaemia, RAPD
Cause:
Arteritis-due to giant cell arteritis – waxy pallor to disc
Non-arteritic- unknown cause, risk factors include those for CVD, sudden drops in BP, small

50
Q

Anterior ischaemic optic neuropathy- giant cell arteritis

A

Inflammation in large/medium vessel walls e.g. ophthalmic artery branches.
Causes loss of vision via central retinal artery occlusion or anterior ischaemic optic neuropathy
Aged 50+
Headache-temporal
Scalp tenderness
Jaw pain
Associated with polymyalgia rheumatica- shoulder and pelvic girdle pain, fatigue
Can also cause CNIII, CNIV or CNVI palsies
Diagnosis confirmed on blood tests: raised c-reactive protein, raised erythrocyte sedimentation rate, raised platelets.

51
Q

Acute painless visual loss- Wet age related macular degeneration (Causes, Risk factors)

A

Cause: Blood vessels grow underneath the retina at the macula causing scarring and bleeding

Risk factors:
Age
Smoking
Disease in the fellow eye

52
Q

Wet age related macular degeneration- Symptoms/signs

A

Symptoms:
Metamorphopsia-look at an Amsler grid of straight lines and they appear wavy and distorted.
Reduction in central vision

Signs: Subretinal fluid or haemorrhage- the new vessels are fragile.

53
Q

Visual loss acute painless- Retinal detachment (Symptoms, risk factors)

A

Symptoms:
Sudden onset flashes and floaters
Progressive visual field defect
Blurred vision

Risk factors:
High myopia
Trauma
Previous eye surgery
Family history
Connective tissue disorders (e.g. Ehlers-Danlos, Stickler, Marfan syndrome)
54
Q

Retinal detachment- signs/management

A

Signs:
Retinal tear or hole
Detached retina
Visual acuity is dependent on the status of the macula

Management: Urgent referral to ophthalmology for surgical repair – within 24 hours if macula on, less urgent if macula off

55
Q

Acute painless visual loss- Vitreous haemorrhage causes

A

Vitreous haemorrhage is bleeding within the vitreous of the eye

Causes:
Trauma
Posterior vitreous detachment
Bleeding from abnormal structures in the eye e.g. diabetic retinopathy

56
Q

Vitreous haemorrhage- signs and symptoms

A

Symptoms:
Sudden onset floaters
Loss of vision->blurred vision (there is a scale of symptoms)

Signs:
Reduced red reflex-it is obscured by blood within the vitreous.
Haemorrhage on fundoscopy-you cannot see the retinal vessels therefore you know the bleeding has occurred in front of the retina.

57
Q

Acute painless visual loss- Stroke/TIA

A

Risk factors: CV risk factors, Coagulopathy/anticoagulant medication

Symptoms:
Sudden visual loss
Potentially in association with other features-dependent on the affected artery/territory

Signs:
Visual field loss affecting both eyes - homonymous hemianopia or quadrantanopia
Ocular examination is typically normal
May have other neurological signs

Management- Refer to stroke team

58
Q

Chronic painless visual loss- Cataracts

A

Cause: Opacification of the lens- the crystallin proteins become clumped together disrupting their usual structure

Symptoms:
A myopic shift in glasses prescription-become more short-sighted
Gradual decline in vision
Glare from bright lights

Signs: Clouding to the lens, Reduced red reflex

59
Q

Chronic painless visual loss- Diabetic retinopathy (Risk factors)

A

Smoking
Hypertension
Duration of diabetes
Diabetic control

60
Q

Diabetic retinopathy- signs/symptoms

A

Symptoms:
Often none until the changes are advanced
Blurred vision

Signs:
Flame retinal haemorrhages (flame-shaped as they track along the nerve fibre layer) this is due to leaking vessels
Dot and blot retinal haemorrhages- localised bleeding
Retinal exudates-proteins from leaky vessels (yellow patches)
Neovascularisation-new vessel formation (look around the optic disc)
Cotton wool spots-axonal debris (fluffy white spots)

61
Q

Chronic painless visual loss- Open angle Glaucoma

A

Symptoms: Often asymptomatic until advanced visual field loss

Signs:
Elevated intraocular pressure
Optic disc cupping
Visual field loss

62
Q

Chronic painless visual loss- Dry are related macular degeneration

A

Cause: Atrophy of the retinal pigmented epithelium (RPE)

Symptoms:
Gradual decline in vision, particularly reading
Mild metamorphopsia- straight lines appear wavy

Signs:
Macular drusen- yellow deposits
RPE hyperpigmentation
Can transform into wet macular degeneration and cause acute vision loss.

63
Q

Chromic painless visual loss- Choroidal tumours (melanoma/metastases)

A
Symptoms:
Flashes or floaters
Blurred vision
Sometimes severe pain depending on the location
Systemic symptoms e.g. weight loss

Signs:
Reduced acuity
Visual field loss
Lesion noted on fundoscopy

64
Q

Chronic painless visual loss- intracranial tumours

A

Symptoms:
Associated neurological symptoms
Loss of visual field
Pituitary tumours (at chiasm) may have pituitary symptoms

Signs:
Visual field loss – depending on location of tumour:
Anterior to chiasm: monocular
At chiasm (pituitary tumour): bitemporal hemianopia
Post-chiasm: homonymous quadrantanopia or hemianopia
May have bilateral swollen optic discs if raised intracranial pressure (papilloedema