Cascade de coagulation Flashcards

1
Q

Quoi compose le complexe prothrombonase?

A
  • FXa + phospholipide

- FVa + Calcium

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2
Q

Quoi compose le complexe tenase?

A
  • FIXa + phospholipide

- FVIIIa + calcium

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3
Q

Quoi compose la lésion tissulaire

A

FIII + FVII + Calcium

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4
Q

Fibrinogène

  1. protéolyse… qui donne 2.
  2. polymérisation…. qui donne 3.
  3. stabilisation
A
  1. protéolyse : monomère fibrine
  2. polymérisation : polymère fibrine
  3. stabilisation : caillot fibrine stable
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5
Q

FIIa active

A

-FVII
-FXI
-fibrinogène
+ calcium -FXIII

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6
Q

FXIIIa active

A

polymère fibrine (devient caillot de fibrine stable)

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7
Q

Comment la voie extrinsèque commence?

A

le facteur tissulaire (d’un tissu endommager) active le FVII

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8
Q

facteur tissulaire et le FVII combiner (FT:VIIa) active quoi?

A

FIX et FX

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9
Q

FXa combien avec quoi pour faire un peu montant de thrombin?

A

FVa

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10
Q

Comment la voie intrinsèque commence?

A

le FXII active avec l’exposition au collagen

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11
Q

quoi active le FXI?

A

FXIIa, HMWK et PK

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12
Q

FXIa active quoi?

A

IX

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13
Q

FIX combiner avec quoi active facteur X?

A

VIII (IXa:VIIIa)

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