cardiovascular week 5 Flashcards

1
Q

What is tidal volume?

A

During normal quiet breathing, about 500ml in and out of lungs with each breath

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2
Q

What is IRV?

A

inspiratory reserve volume

the amount of air that can be inspired past tidal volume

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3
Q

What is ERV?

A

expiratory reserve volume

the amount of air that can be expired after tidal expiration

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4
Q

What is residual volume/

A

after the most strenuous expiration, about 1200ml of air remains in the lungs

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5
Q

What is IC?

A

inspiratory capacity

the total amount of air that can be inspired after tidal expiration

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6
Q

What is FRC?

A

The functional residual capacity

the amount of air in the lungs after tidal expiration

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7
Q

What is VC?

A

vital capacity

the total amount of exchangeable air

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8
Q

What is TLC?

A

total lung capacity
the some of all lung volumes
usually about 6L in males

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9
Q

What is FEV1?

A

Forced expiratory volume in one second

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10
Q

What is FVC?

A

forced vital capacity

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11
Q

Describe the ratio of FEV1/FVC

A

expressed as a percentage
reduced in obstructive diseases
sustained in restrictive

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12
Q

What is peak respiratory flow?

A

maximum expiratory flow that can be sustained for a minimum of 10ms

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13
Q

What is COPD?

A

chronic obstructive pulmonary disease

name for a collection of lung diseases including chronic bronchitis, emphysema and chronic obstructive airways disease

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14
Q

What are the typical symptoms of COPD?

A

increasing breathlessness when active
persistent cough with phlegm
frequent chest infections
other signs - weight loss, tiredness, swollen ankles

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15
Q

What causes COPD?

A

mainly smoking
smoking irritates and inflames the lungs which result in scarring
inflammation leads to permanent changes in the lung - walls of airway thicken, more mucous is produced
damage to the delicate walls of the lungs causes emphysema and the lungs to lose their normal elasticity
smaller always become scarred and narrowed

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16
Q

What are rarer causes of COPD?

A

fumes
dust
air pollution
genetic disorders

17
Q

What is emphysema?

A

an abnormal enlargement of the alveolar airspaces distal to the terminal bronchi

18
Q

What are the four types of emphysema?

A

centrilobular
pan lobular
paraseptal
irregular

19
Q

What are the three primary systems that regulate the H+ concentration of the body fluids to prevent acidosis or alkalosis?

A

the chemical acid-base buffer systems of the body fluids, which immediately combine with an acid or base to prevent excessive changes in H+ concentration
The respiratory centre, which regulates the removal of CO2 from the extracellular fluid
the kidneys, which can excrete either acid or alkaline urine

20
Q

What are the fast acting lines of defence against changes in body pH?

A

buffer systems

respiratory system

21
Q

What is the more slowly acting defence against changes in pH?

A

The kidneys (hours to days)

22
Q

What are the main buffer systems?

A

bicarbonate

proteins - haemoglobin

23
Q

What can cause respiratory acidosis?

A

impaired lung function

24
Q

How does emphysema cause acidosis?

A

less CO2 expiration
build up of CO2
build up of H+
acidosis

25
Q

What is the kidney’s response to alkalosis?

A

secrete less H+

fail to resorb all filtered HCO3-

26
Q

What are the three ways that the kidneys respond to acidosis?

A

secretion of H+
resorption of filtered HCO3-
production of new HCO3-

27
Q

How can COPD be differentiated from asthma?

A

COPD should not be reversible with bronchodilator
asthma would respond to BD in terms of FEV1 volume
gas transfer would be reduced in COPD but not in asthma

28
Q

Describe obstructive respiratory condtions

A

rate of flow is reduced

29
Q

Describe restrictive lung conditions

A

rate of flow is normal but lung volumes are reduced