Cardiovascular Therapeutics EMQs

Question 1

What drug is an effective ventricular anti-arrhythmic agent, preferably one that will act quickly and be given IV to effect?

Answer 1

Best = lignocaine.

Question 2

When is Quinidine indicated in the treatment of cardiac disease?

Answer 2

in the absence of significant structural heart disease and with a normal HR, this a reasonable candidate for attempting to convert back to sinus rhythm.

Question 3

Which drug is the most effect anti-hypertensive in the cat?

Answer 3

Amlodipine

Question 4

What drug should you give to cats that are at risk of ATE (due to HF associated with HCM)?

Answer 4

Clopidogrel (to inhibit clot formation although will not completely prevent thrombi formation in the first instance)

Question 5

Mechanism - Amlodipine

Answer 5

Ca channel blocker –> vasodilation and improves BF

Question 6

Mechanism - Benazepril

Answer 6

ACEI so used for Tx – hypertension, CHF, preventing renal and retinal complications of DM

Question 7

What type of drug is digoxin?

Answer 7

A cardiac glycoside

Question 8

Uses of digoxin?

Answer 8

Used in heart rhythm disorders and HF. Used to slow HR in AF.

Question 9

Mechanism - Pimobendan

Answer 9

Calcium sensitiser and a PDE 3 inhibitor. Overall causes vasodilation and is a positive inotrope.

Question 10

What is sotalol?

Answer 10

Non-selective competitive beta-adrenergic receptor block.

Class 3 anti-dysrhythmic. Used to treat arrhythmias and hypertension.

Question 11

What is spironolactone

Answer 11

K-sparing diuretic