Cardiovascular System Flashcards
The outer layer of the heart is the __________
Pericardium
The middle layer of the heart is the __________
Myocardium
The innermost layer of the heart is the __________
Endocardium
(1) A normal adult heart rate is __ - ___ bpm.
(2) Tachycardia is >___bpm
(3) Bradycardia is
(1) 60 - 100 bpm
(2) >100 bpm
(3) <60 bpm
What does depolarisation mean?
Contraction
The (1) ___ wave on an ECG represents atrial depolarisation and the (2) __ ____ is responsible for this
(1) P wave
(2) SA node
The P-Q segment on an ECG represents ___________ (long answer).
The time the signal travels from the SA node to the AV node.
The QRS complex on an ECG represents _______ ____________ - The AV node fires off electrical impulses down the bundle of His, through the right and left ventricular branches, ad through the purkinje fibres.
Ventricular Depolarisation (contraction).
The ____ wave on an ECG represents ventricles contracting and pump blood out
S-T
The T wave on an ECG represents _________ ____________
Ventricular Repolarisation
What does repolarisation mean?
Relaxation
The __________ is the thoracic cavity that the heart sits in.
Mediastinum
The ________ _____ is the right semilunar valve.
Pulmonary valve
The ______ _____ is the right atrioventricular valve.
Tricuspid valve
The _____ _____ is the left semilunar valve
Aortic valve
The ______ _____ is the left atrioventricular valve
Mitral valve
The ______ ________ is Fibrous cords of connective tissue that connect the papillary muscles to the tricuspid valve and mitral valve (AV valves). It stops the AV valves from letting blood flow back into the ventricles.
Chordae Tendinae
The pulmonary artery carries __________ blood
Deoxygenated
The pulmonary vein carries __________ blood
Oxygenated
The left and right (1) ________ ______ supply blood to the heart, more specifically the myocardium. They branch off from the (2) _____, just above the semilunar valves, and sit on top of the heart like a crown.
(1) Coronary arteries
(2) Aorta
Diastole = ______
Relax
Systole = _______
Contract
The first stage of the cardiac cycle: ______ ______ - All chambers are relaxed, they start to fill up with blood from the inferior and superior vena cavae (right), and from the pulmonary veins.
Cardiac Diastole
The second stage of the Cardiac cycle: _____ _______, __________ _________ -
Blood empties into the ventricles to equalise the pressure. Blood stops flowing when 70%ish of the blood is in the ventricles. The atria contract, pushing the other 30% into the ventricles.
The atria then relaxes, and the Ventricles contract, closing the AV nodes.
Atrial Systole, Ventricular Diastole
The third stage of the Cardiac cycle: _____ _______, __________ _________ - The high pressure in the ventricles cause the SL valves to open, so the blood flows into the aorta and pulmonary arteries.
The ventricles relax, thereby decreasing the pressure, pulling the SL valves closed. The decrease in pressure causes the blood to flow backwards, but the SL valves stop a back flow.
Atrial Diastole, Ventricular Systole
The amount of blood pumped through the circulatory system in 1 minute is known as (1) ______ _______. This is calculated as (2) _____ ______ x _____ ____ = ___ __ __
(1) Cardiac Output
(2) Stroke Volume x Heart Rate = ?litres per minute
____ _______ is the amount of blood pumped out in a single contraction/heartbeat (litres).
Stroke volume
____ ___ is the number of times the heart beats per minute
Heart rate
_____ _______ is the force of blood pushing against the arterial wall.
Blood pressure
(1) ________ blood pressure is the highest pressure and (2) ________ blood pressure is the lowest pressure.
(1) Systolic
(2) Diastolic
An erythrocyte can carry approximately __ _______ haemoglobin molecules
280 million
A haemoglobin molecule can carry _ oxygen molecules
4
The three types of Granulocytes are: (1) ________, (2) _________, and (3) _________.
(1) Neutrophils
(2) Basophils
(3) Eosinophils
The two types of Agranulocytes are (1) __________ and (2) __________
(1) Monocytes
(2) Lymphocytes
_________ is the cessation (stopping) of bleeding
Haemostasis
__________ should always be administered through a large bore cannula due to its caustic nature?
Amiodarone
The maximum dose of Clopidogrel is (1) ____mg for Thrombolysis, (2) _____mg for PPCI.
(1) 300mg
(2) 600mg
The 3 indications of Clopidogrel are (1) _____, (2) ______ or (3) _________ ___________
(1) STEMI
(2) PPCI
(3) Thrombolytic treatment.
STEMI stands for _____ __-______ _________ ________.
Acute ST-elevated Myocardial Infarction
PPCI stands for ______ ________ _________ _________ - and it is a procedure used to treat the narrowed coronary arteries of the heart and angina in patients.
Primary Percutaneous Coronary Intervention.
The 3 contraindications of Clopidogrel are (1K) _____ _______, (2S) ______ ________ _________ and (3A) ________ _______ _________ (such as a peptic ulcer).
(1) Known allergy
(2) Severe liver impairment
(3) Active pathological bleeding
GTN comes as a sublingual spray (___mcg). There is no max dose.
400
___ ______ is used for cardiac chest pain due to angina or MI, when systolic BP is >90mmHg or breathlessness due to pulmonary oedema.
GTN spray
The 7 contraindications of ______ are hypotension, hypovoleamia, head trauma, cerebral haemorrhage, sildenafil use, unconscious patient, or known severe aortic / mitral stenosis.
GTN
The 2 side effects of ________ are wheezing in some asthmatics and increased risk of gastric bleeding.
Aspirin
Clopidogrel inhibits ______ _________
Platelet aggregation
The 4 side effects of Clopidogrel are: (1) _______, (2) _________ ___, (3) _______ and (4) _______ (GI and intercranial)
(1) Dyspepsia
(2) Abdominal pain
(3) Diarrhoea
(4) Bleeding
The pharmacodynamics of GTN show that it is a _________ drug - as it dilates the coronary arteries / systemic veins.
Vasodilator
The 3 potential side effects of GTN are: (1H) ________, (2D) _________ and (3H) __________
(1) Headache
(2) Dizziness
(3) Hypotension.
(1) The maximum dose of Aspirin is ____mg (1 tablet)
(2) Aspirin comes in the form of a ________ or ________ tablet
(1) 300mg
(2) Dispersible or Chewable tablet
The indications of Aspirin are (1) ________ _________ or (2) ________.
(1) Myocardial Infarction or
(2) Ischaemia.
The 4 contraindications of ________ are children under 16, active GI bleeding, hemophilia of other blood clotting disorders, severe hepatic disease.
Aspirin
Platelet cells are also known as ____________
Thrombocytes
The brief pause between the P waves and the QRS complex represents a momentary conduction delay at the ___ _____
AV node
Prothrombin Activator (common pathway) can be formed by two processes which often occur together: the (1) __________ __________ and the (2) __________ _________
(1) Intrinsic pathway
(2) Extrinsic pathway
__________ is the breakdown of fibrin in blood clots
Fibrinolysis
GTN is not administered orally because it is completely destroyed by the process of ______ _____ ____________
First Pass Metabolism
The backflow of blood into the atria during ventricular contraction is prevented by the ______________ _______
Atrioventricular valves
The ______ ______ layer of the blood vessel is made up of elastic fibres and muscle and provides strength and contractility.
tunica media
The benefits of Clopidogrel in an emergency situation mean that it can be administered with caution in __________
pregnancy
What percentage of blood is made up of red blood cells?
approx 45%