Cardiovascular physiology Flashcards

1
Q

Layers of the heart

A

• pericardium (sac around the heart)
• epicardium (outer surface)
• myocardium (heart muscle)
• endocardium (inner lining)

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2
Q

Properties of a cardiac muscle

A

•rhythmicity
• excitability
• contractility
• conductivity

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3
Q

Cardiac Action Potential

A

0 = Na+ (in)
1 = K+Cl (out)
2 = Ca2 (in)
K+ (out)
3 = K+ (out)
4 = resting potential

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4
Q

Cardiac output - Stroke volume

A

Volume of blood pumped by each ventricle in one contraction. Approx. 70ml

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5
Q

What is Cardiac Output (CO)

A

Amount of blood pumped by the heart in one minute.
CO = (heart rate [HR] x stroke volume [SV])

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6
Q

Blood pressure during cardiac output

A

BP = (cardiac output [CO] x Total peripheral resistance [TPR])

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7
Q

Which heart chambers does blood flow into on its return from the rest of the body?

A

Right atrium, into Right Ventricles

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8
Q

Name the heart valves between:

Right atria and Right Ventricle

Right Ventricle and Pulmonary artery

Left Atria and Left Ventricle

Left Ventricle and Aorta

A

Tricuspid

Pulmonary (Semilunar)

Mitral

Aortic (Semilunar)

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9
Q

What is the anatomical landmark for auscultation of the aortic valve

A

Right sternal border, second intercostal space

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10
Q

What is the relative voltage of the cardiac cell membrane at rest?

A

-90mV

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11
Q

What changes the action potential of cardiac cells?

A

Movement of positively charged ions into the cell until it increases to -40mV

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12
Q

Describe the path of electrical impulses through the heart?

A

Starts at the sinoatrial node, through the atria, to the atrioventricular node, down the left and right bundle branches, to the perkinje fibres

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13
Q

ECG:

What electrical action does the P wave relate to?

A

Atrial Depolarisation

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14
Q

ECG:

What does the QRS complex relate to?

A

Ventricular depolarisation

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15
Q

ECG:

What does the T Wave represent?

A

Ventricular Repolarisation

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16
Q

ECG:

What is a PR interval, and what is the normal range?

A

The gap between the start of the P wave and the start of the QRS complex, usually between 120 - 200ms

17
Q

Heart sounds are often described as “Lub-Dub”, what causes the “Lub” sound?

A

Closing of the Atrioventricular valves during isometric contraction of the ventricles

18
Q

What simple and fast response does the body do to compensate for falling blood pressure?

A

Raise heart rate

19
Q

What is preload

A

Blood volume in the ventricles before contraction