Cardiovascular Disease - Rheumatic Fever Flashcards
1
Q
other name for Strep pyogenes
A
Group A beta-hemolytic strep (GABHS)
2
Q
two bacteria strongly associated with low socio-economic status
A
GABHS H. pylori
3
Q
major criteria for rheumatic fever
A
- polyarthritis
- carditis
- subcutaneous nodules
- erythema marginatum
- sydenham chorea
4
Q
most common initial presentation of rheumatic fever
A
polyarthritis
5
Q
most specific presentation of rheumatic fever
A
sydenham chorea
6
Q
most serious presentation of rheumatic fever
A
carditis
7
Q
manifestation of carditis in rheumatic fever
A
- pericardial friction rub
- weak heart sounds
- tachycardia
- arrhythmias
- mitral regurgitation
8
Q
pathologic lesion in rheumatic heart disease
A
- Anitschkow Cells/Caterpillar cells (macrophages containing abundant cytoplasm, round nuclei with slender, wavy ribbon of chromatin)
- May coalesce to form Aschoff Giant Cells that together with T cells and plasma cells form Aschoff bodies
9
Q
Other pathologic findings in rheumatic heart disease
A
- Fibrinoid pericarditis (bread-and-butter pericarditis)
- MacCallum Plaques: irregular thickening of the subendocardium
- Fish-mouth/buttonhole stenosis
- mitral stenosis
