Cardiovascular 1 Flashcards

1
Q

order of contraction in heart

A
SA node
AV node
bundle of his
right bundle branch
left bundle branch
purkinje fibers
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2
Q

depolarization vs repolarization

A

contraction vs relaxation

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3
Q

phase 0

A

rapid depolarization

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4
Q

phase 1

A

beginning of repolarization

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5
Q

phase 2

A

plateau

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6
Q

phase 3

A

rapid repolarization

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7
Q

phase 4

A

slow depolarization

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8
Q

most important ions in maintaining rhythm

A

K and Ca

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9
Q

relative refractory period

A

only period where a cell can initiate its own action potential
occurs during end of phase 3

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10
Q

absolute refractory period

A

period during action potential where cell can not stimulate action potential
occurs during phases 1, 2, 3

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11
Q

p wave

A

atrial depolarization

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12
Q

pr interval

A

how long it takes nerve impulse to get from SA nose to AV node to ventricular depolarization

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13
Q

PR segment

A

impulses through AV node until ventricular depolarization

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14
Q

QRS wave

A

ventricular depolarization

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15
Q

ST segment

A

between ventricular depolarization and repolarization, part of absolute refractory period

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16
Q

T wave

A

ventricular repolarization

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17
Q

when does congestive heart failure occur

A

normal activity or at rest

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18
Q

left ventricular failure “pulmonary congestion” symptoms

A

dyspnea, orthopnea, tachypnea, pulmonary edema, cough, nocturnal dyspnea

19
Q

right ventricular failure “venous congestion” symptoms

A

pitted edema, ascites

20
Q

congestive heart failure, right and left sided, symptoms

A

arrhythmias-death

21
Q

congestive heart failure therapy options

A

cardias glycosides lanoxin (Digoxin®)
general vasodilators
diuretics

22
Q

types of general vasodilators

A

nitrates- venodilators
hydralazine (Apresoline®)- arterial dilators
ACE inhibitors arterial and venodilators
angiotensin receptor blockers (ARBs)- arterial and venodilators
non selective BB- carvedilol (Coreg®) due to alpha 1 blockade

23
Q

uses for cardiac glycosides

A

CHF, arrhythmias

24
Q

MOA of cardiac glycosides

A

decrease heart rate, increase FOC, slow conduction through AV node

25
side effects of cardiac glycosides
N/V/D, loss of appetite, vision problems, confusion, dizziness
26
conditions when taking cardiac glycosides that pre-dispose to digitalis toxicity
hypokalemia, hypercalcemia
27
do not give cardiac glycoside (digixon (Lanoxin®)) if
pulse is less than 60
28
digitalis toxicity
cardiac- slow irregular pulse CNS- confusion, HA, delirium, vision changes, halos around dark object GI- N/V/D
29
digoxin therapeutic serum level
.5 to 2 ng/mL toxic- >2.5ng/mL onset- rapid and short duration of action
30
treatment of digitalis toxicity
discontinue drug, take serum level tests to see if K levels are low, K may be given to strengthen hearts ability to beat regularly (K-Dur)
31
vasodilators
dilate veins and arteries decrease BP, blood preload and after load decrease oxygen demand increase CO
32
main goal of vasodilators
increase CO
33
what happens when organs receive less oxygen/blood from heart
brain- dizziness, drowsiness, less alert lungs- SOB, coughing kidneys- retain more water causing edema everywhere and in lungs- given diuretic
34
2 types of dosing cardio tonic drugs
digitalizing dose and maintenance dose
35
digitalizing dose
frequent and higher dose given to achieve desired blood levels
36
maintenance dose
smaller regular doses given once/day to maintain blood levels
37
positive inotropic
increases FOC | ex- cardiotonics/cardiac glycoside
38
negative inotropic
decrease FOC | ex- BB, calcium channel blockers
39
positive chronotropic
increase HR | ex- epinephrine (EpiPen®) and (Atropine®)
40
negative chronotropic
decrease HR | ex- cardiac glycoside
41
positive dromotropic
increase conduction velocity | ex- epinephrine (EpiPen®)
42
negative dromotropic
decrease conduction velocity | ex- cardiac glycoside
43
the 6 rights
patient, drug, dosage, route, time, documentation