Antihyperlipidemic Drugs Flashcards
hyperlipidemia
increase in cholesterol and triglycerides in blood atherosclerosis
what can artherosclerosis lead to
CAD, angina, CHF, MI, stroke, PAD, RAI
lipoproteins
help carry cholesterol
good cholesterol
HDL
bad cholesterol
LDL, VLDL
LDL cholesterol levels should be
below 100 mg/dl
VLDL cholesterol levels should be
below 30 mg/dl
HDL cholesterol levels should be
greater than 60 mg/dl
triglyceride levels should be
less than 150 mg/dl
what happens if HDL is too low (below 40 mg/dl)
increase risk of heart disease
total cholesterol levels should be
less than 200 mg/dl
lifestyle modifications
increase exercise, decrease caloric intake, change diet (less fat more fiber), increase omega 3 fatty acids
foods high in cholesterol
organ meats, egg yolks, full fat dairy
types of antihyperlipidemics
vitamin b-3, HMG Co A Reductase Inhibitors-RX
what do all HMG Co A Reductase Inhibitors-RX end in
statin
vitamin b-3 side effects
skin flushing/pruritus, GI distress, blurred vision, glucose intolerance, PUD, hepatotoxicity
HMG Co A Reductase Inhibitors-RX aide effects
GI distress, HA, myalgia, lead to liver failure, interaction with grapefruit and Lipitor
cholesterol medications categories
bile acid sequestrants-RX, fibrin acid derivatives, cholesterol absorption inhibitor
bile acid sequestrants-RX side effects
constipation/bloating, fiber can help reduce SE
fibrin acid derivatives side effects
GI distress, rhabdomyolysis is increased when combined with a statin
cholesterol absorption inhibitor side effects
mild GI distress
drug of choice for most patients at risk for coronary and other atherosclerotic vascular diseases
statins
what do statins decrease
incidence of major coronary events and death in patients with risk for coronary and other atherosclerotic vascular diseases
