Cardiopulmonary A&P Flashcards
What structures does the right coronary artery supply?
-RT atrium and ventricle
-inferior wall of LT ventricle
-AV and SA node (60% population)
-bundle of his
What structures does the LT coronary artery supply?
-“the widow maker”
-LT anterior descending (LT ventricle, septum, inferior apex)
-LT circumflex (lateral and inferior walls of LT ventricle, SA node)
Name the 5 layers of the heart from outer to inner
fibrous pericardium, parietal pericardium, visceral pericardium (epicardium), myocardium, endocardium
Where is the pericardial cavity?
Between the parietal pericardium and visceral pericardium (epicardium)
What is the serous pericardium composed of?
visceral and parietal pericardium
4 main characteristics/functions of myocardium
-Automaticity: pacemaker cells keep heart moving w/o conscious voluntary control
-Conductivity: gap junctions between myocytes allow them to depolarize as a group
-O2 demand
-Contractility: affected by sympathetic stimulation, hormonal circulation, preload and afterload
What are the 4 main valves? Describe their location
-tricuspid (atrioventricular): RT atrium and RT ventricle
-mitral (atrioventricular): LT atrium and LT ventricle
-pulmonary (semilunar): RT ventricle and pulmonary artery
-aortic (semilunar): LT ventricle and aorta
Describe the blood flow of deoxygenated blood to lungs
deoxygenated blood from vena cava -> RT atrium -> through tricuspid valve -> RT ventricle -> pulmonary valve -> pulmonary artery -> lungs
Describe the blood flow of oxygenated blood
oxygenated blood through pulmonary veins -> LT atrium -> through mitral valve -> LT ventricle -> aortic valve -> aorta -> body
Equation for hemodynamics
CO = HR x SV
CO - cardiac output
HR - heart rate
SV - stroke volume
What is cardiac output? At rest rate?
Amount of blood ejected out of the LT ventricle into the body per minute
at rest, 4-5 L/min
What is stroke volume? Rate?
Amount of blood ejected out of the LT ventricle per beat
SV = end diastolic volume (EDV) - end systolic volume (ESV)
55-100mL/beat
What 3 things affect SV? Briefly describe each
Preload: “EDV”; amount of filling and stretch on cardiac muscle pre-contraction
Afterload: force LT ventricle generates to overcome aortic pressure to open aortic valve (resistance heart contraction pushes against); inversely related to SV
Contractility: force of cardiac contraction in Lt ventricle (affected by sympathetic stimulation and O2 supply)
What is Frank-Starling Law?
-cardiac contractility is dependent on preload
-increased cardiac contractility results in greater stroke volume
the greater the EDV, the greater the stx and volume pumped
What is ejection fraction (EF)? Normal range? Equation? Low EF indicator of what?
Percentage of blood emptied from ventricle during systole; 60-70%
EF = SV/LVEDV
Indicator of cardiomyopathy or heart failure
What influences does sympathetic stimulation (adrenergic) have on heart?
-control in medulla via T1-T4
-SA node, AV, conduction pathways
-increases HR, force of myocardial contraction, O2 demand
-coronary artery vasodilation
What influences does parasympathetic stimulation (cholinergic) have on heart?
-control in medulla via vagus nerve, cardiac plexus
-innervates SA and AV nodes
-slows rate and force of myocardial contraction, less O2 demand
-coronary artery vasoconstriction
Chemoreceptor location and function
found in carotid body; sense CO2, O2, and pH which affect HR and RR (also affect sympathetic and parasympathetic stimulation)
Where are baroreceptors found?
aorta and carotid sinus
What does the circulatory reflex respond to? Describe what happens w/ increased and decreased BP
BP changes
Increased BP - parasympathetic stimulation; decreases rate and force of contraction
Decreased BP - sympathetic stimulation, increased HR and BP, vasoconstriction