cardiomyopathy Flashcards

1
Q

how to you calculate cardiac output

A

HR x SV

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2
Q

how do you calculate stroke volume

A

edv-esv

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3
Q

Which layer of the heart are the coronaries found in

A

epicardium

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4
Q

What layer of the heart is the electrical system found in

A

Myocardium

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5
Q

What does a positive chronotrope do

A

increase heart rate

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6
Q

What does a negative chronotrope do

A

lower heart rate

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7
Q

What factors increase heart rate

A

Sympathetic system
Hyperthyroidism
hypoxemia / acidosis
Meds

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8
Q

what factors decrease heart rate

A

parasympathetic
athletes
meds

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9
Q

What factors determine the stroke volume

A

end diastolic volume
&
end systolic volume

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10
Q

What is ejection fraction determined by

A

the blood volume that get pumped out with each heart beat
*should be half the volume in the ventricle

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11
Q

What determines how much blood volume a ventricle can hold

A

degree of myocyte stretch

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12
Q

What is the Frank Starling curve

A

A curve that shows the optimal contractility / expansion of the heart

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13
Q

What is the most common referencing disease process of the LV

A

Cardiomyopathy

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14
Q

What is cardiomyopathy

A

disease process that changes the cardiac structure (effects myocardium itself)

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15
Q

What are the different types of cardiomyopathy

A

hypertrophic
dilated
arrythmogenic
restrictive
unclassified

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16
Q

What are the most common causes of cardiomyopathy

A

genetic (most common)
mixed
acquired

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17
Q

What is takotsubo

A

broken heart syndrome

*catecholamine surge that causes ventricular ballooning

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18
Q

What is the classification system of cardiomyopathy

A

M O G E S classification

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19
Q

What is the MOGES classification

A

Morphofunctional
Organ involvement
Genetic predisposition
Etiologic definition
functional status

20
Q

What is systolic dysfunction

A

decreased contractility leading to reduced EF

21
Q

What generally causes systolic disfunction

A

Dilated cardiomyopathy

22
Q

What is diastolic dysfunction

A

inability for the ventricle to completely relax to allow for appropriate passive filling

23
Q

What generally causes diastolic dysfunction

A

hypertrophic cardiomyopathy
restrictive cardiomyopathy

24
Q

What occurs in the heart with dilated cardiomyopathy

A

eccentric hypertrophy which causes the ventricles to dilate

the excessive dilation with lead to reduced contractility

25
As the LV dilates, what are the downstream effects on the heart
Increase pre-load cause increased atrial pressure and finally atrial dilation
26
What is the most common cause of right sided heart failure
left sided heart failure
27
how does the body try to compensate for decreased cardiac output
RAAS
28
What is pheochromocytoma
Tumor arising from catecholamine producing cells in the adrenal gland
29
When is Takostubo classically seen
postmenopausal women
30
What is S3 heart sound associated with
maximum compliance of the LV
31
What makes the S3 sound
Sound of the blood from the LA striking the dilated LV
32
What is hypertrophic cardiomyopathy
Thickened myocardium leading to poor diastolic filling
33
What are some causes of hypertrophic cardiomyopathy
genetic chronic hypertension aortic stenosis amyloidosis
34
What is concentric hypertrophy
sarcomeres are stacking and getting thicket *genetic abnormalities are generally associated
35
What is HOCM
hypertrophic obstructive cardiomyopathy *sudden cardiac death (most commonly in athletes)
36
What occurs in the heart with HOCM
LV hypertrophy along the septum begins to occlude the outflow tract as this tract narrows, a vacuum can form which decreases CO
37
What heart sound is associated with hypertrophic cardiomyopathy
S4 *harsh crescendo/decresendo as it hits the outflow obstruction
38
What is occurring with restrictive cardiomyopathy
fibrosis of the myocardium
39
What is compliance
ability of myocytes to stretch
40
What type of murmur can occur from restrictive cardiomyopathy
systolic from regurgitation
41
What are some of the causes of restrictive cardiomyopathy
end-myocardial fibrosis radiation fibrosis amyloidosis sarcoidosis hemochromatosis
42
What population is restrictive cardiomyopathy most common in
children in developing countries
43
What is sarcoidosis
An autoimmune disease form of restrictive cardiomyopathy
44
What disease processes is hallmarked by non-caseating granuloma formation
Sarcoidosis
45
Where do the non-caseating granulomas in sarcoidosis deposit
Lungs Heart Eyes Skin