Cardiology 2 Flashcards

1
Q

Management of COMPENSATED acute heart failure (pulmonary oedema)

A

Sit up
Oxygen if sats <94

IV Furosemide

SC Morphine

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2
Q

Advanced managemnt of acute heart failure

A

CPAP

IV Furosemide over 24hr

IV Dopamine over 24hr (inhibits SNS - increases myocardial contractility)

Intra-aortic balloon pump if in shock

Ultrafiltration if diuretics CI

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3
Q

Criteria for cardiac resynchronisation therapy

A

Symptomatic despite full medical management of ACEi, BB, Furosemide, Ivadbradine, Spironolactone, Hydralazine (if afro-carib)

1) LBBB on ECG
2) LVEF <30%
3) NYHA III

4) QRS >130ms

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4
Q

NYHA Classification of Heart Failure

A

I - no physical limitations

II - slight limitation, comfort at rest

III - marked limited activity, comfort at rest

IV - discomfort at rest

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5
Q

Pt is admitted with worsening SOB. RR 30, sats 91%, pulse 90bpm.

ECG shows normal sinus rhythym with a narrow QRS complex. LVEF 25%.

Current meds are Ramipril, bisoprolol, spironolactone, Bumetanide, Atorvastatin, Aspirin and Isosorbide Mononitrate.

She is treated with IV Furosemide. What intervention should she receive after her acute management? (+ other indications for this management)

A

Implantable cardioverter-defibrillation (ICD)

  • LVEF <35%
  • Good QoL
  • Ventricular Fibrillation or Ventricular Tachycardia
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6
Q

Management of DECOMPENSATED acute heart failure (pulmonary oedema) secondary to Atrial Fibrillation

A

IV METOPROLOL (Beta-blockade, unless asthma/ COPD)

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7
Q

Pt presents with syncope and palpitations. ECG shows a long QT interval.

Congenital cause of Long QT Syndrome

Acquired cause of Long QT Syndrome

Treatment of Long QT?

A

Congenital: Jervell-Lange-Nielsen syndrome (mut. Cardiac Na/K channels)

Acquired: HypoK, HypoCa, amiodarone, TCAs, bradycardia, MI, diabetes

Tx:
Underlying
+ IV Isoprenaline if acquired

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8
Q

Pt presents with 2hrs of palpitations and malaise. Her pulse is 140bpm but other vitals are normal. She is haemodynamically stable.

ECG reveals regular tachycardia with QRS duration 80ms.

Diagnosis? 1L management? 2L Management?

What would the management be if she were haemodynamically unstable?

A

Narrow QRS = Supraventricular Tachycardia, haemodynamically stable

1L Vagal manoeuvre

  • carotid sinus massage
  • blowing into empty syringe

2L IV Adenosine

3L BB

If haemodynamically unstable: DC Cardioversion

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9
Q

Pt’s ECG shows a series of broad QRS complexes and tachycardia. There are no abnormalities on examination.

What is the most appropriate management?

A

Broad QRS = Ventricular tachycardia

No abnormalities = stable

Tx: IV Amiodarone 300mg (Then 900mg over 24hrs)

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10
Q

Pt’s ECG shows a series of broad QRS complexes and tachycardia. He has no pulse.

What is the most appropriate management?

A

= ventricular tachycardia but really bad

Chest compressions + unsynchronised shock

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11
Q

Pt’s ECG shows a series of broad QRS complexes and tachycardia. He has a pulse but has experiences two episodes of syncope.

What is the most appropriate management?

A

= unstable ventricular tachycardia

DC Cardioversion (Synchronised)

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12
Q

Pt presents with palpitations. Their ECG has a corkscrew appearance. She recently has been taking clarithromycin and amoxicillin to treat CAP.

Likely diagnosis?

A

Torsades des pointes (Ventricular Tachycardia)

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13
Q

Pt presents with tachycardia and ECG shows broad QRS complexes. They have had palpitations for 5hrs. There are no signs of oedema or raised JVP.

Likely diagnosis? Management?

A

Haemodynamically stable Sustained Ventricular Tachycardia

IV Amiodarone

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14
Q

Asthmatic pt presents with SOB and palpitations. ECG shows supraventricular tachycardia of 180bpm.

How should we slow the rate to be able to identify the arrhythmia?

A

Asthmatic :. adenosine contraindicated

Therefore VERAPAMIL

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15
Q

Pt presents with SOB and palpitations. ECG shows supraventricular tachycardia of 180bpm.

How should we slow the rate to be able to identify the arrhythmia?

A

ADENOSINE

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16
Q

What is the most common ECG finding in pulmonary embolism?

A

Sinus tachycardia

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17
Q

Pt presents with a fast irregular pulse and muscle weakness. Their breathing is deep and slow (Kussmaul’s). THeir ECG shows progresdive abnormalities, including tall T-waves.

Likely diagnosis? Investigations? What other ECG abnormalities might you expect? Treatment?

What are the complications of this?

A

Hyperkalaemia

Serum K+ >5.5mmol/L

ECG:

  • progressive
  • Tall T wave
  • SMALL P-WAVE
  • WIDE QRS

Non-urgent: stop offender (ACEi, spironolactone, NSAID) + POLYSTYRENE SULFONATE RESIN (binds K+ in gut)

Urgent: K>6.5

  • IV CALCIUM GLUCONATE
  • IV ACTRAPID + GLUCOSE
  • IV SALBUTAMOL

Complications:

  • Ventricular fibrillation
  • heart failure
18
Q

Wolf-Parkinson-White ECG

Pathophysiology

A

= Atrioventricular Re-entry Tachycardia
Wide QRS
Short PR
Delta Wave

Accessory pathway > re-entrant loop > supraventricular tachy

19
Q

Types of Supraventricular Tachycardia

A

1, Atrioventricular Nodal Re-entrant: re-entry back through AVN

  1. Atrioventricular Re-entrant: re-entry via accessory pathways (WPW)
  2. Atrial tachycardia: signal originates in atria but not SAN
20
Q

Normal PR interval

A

0.12-0.20s

21
Q

PR depression

A

Pericarditis

22
Q

Short PR in an arrhythmia

A

Wolf Parkinson White

23
Q

Normal QRS range

A

0.08-0.12s

24
Q

Wide QRS

A
RBBB/ LBBB
Hyperkalaemia (sine) 
WPW 
Ventricular rhythm
TCA poisoning
25
Q

HASBLED

A

Risk of bleeding for patients on anticoagulants

26
Q

Heart failure

  • medications that improve prognosis
  • medications that give symptomatic relief
A

Prognostic improvers
- ACEi
- BB
(start at different times!)

Symptomatic relief:
- Diuretics

27
Q

Furosemide pharmacology

A

Loop Diuretic

Inhibits Na/K/Cl transporter on ASCENDING limb

28
Q

K-sparing diuretics pharmacology

A

eg Amiloride, Spironolactone

Inhibit ENaC on DCT

29
Q

Thiazide diuretics pharmacology

A

eg Bendroflumethiazide

Inhibit Na/Cl transporter in DCT

30
Q

MI Complications

A

DARTH VADER

Death
Arrhythmia
Rupture (V.septum/papillary muscles) 
Tamponade
Heart failure 
Valve disease 
Aneurysm of ventricle
Dressler's syndrome 
Embolism 
Regurgitation (mitral)/ recurrence
31
Q

Pansystolic murmur loudest at apex

Diagnosis? Cause?

A

Mitral Regurgitation

Poor supply to papillary muscles/ septum > rupture > valve incompetence

32
Q

Complication of acute severe mitral regurgitation

A

Acute pulmonary oedema - SOB

33
Q

HMG CoA reductase inhibitors are what type of medication?

A

Statins

34
Q

Warfarin pharmacology

A

Vitamin K antagonist

Avoid spinach

Grapefruit helps

35
Q

When is pericardiocentesis indicated in pericarditis?

A
  • BACTERIAL cause

or complication:

  • cardiac tamponade
  • pericardial effusion
36
Q

Complications of pericarditis

A
  • Cardiac tamponade
  • Pericardial effusion
  • Constrictive pericarditis
37
Q

ECG serial changes in Pericarditis from week 1-8

A

1-3wks - T-wave flattens

3-8wks - T-wave inverts

8+wks - Normal ECG

38
Q

Pericarditis ECG

A

= GOLD standard

Diffuse Saddle ST-elevation + PR depression

39
Q

Pt presents with sharp pleuritic pain that is worse on inspiration and when lying on their back (supine). They have a low-grade fever and are unable to shake off a hiccup.

On auscultation, there is a “squeaky” sound.

Likely diagnosis? Investigations? Management?

A

Pericarditis, probably S. pyogenes (Lancefield Group A B-haemolytic)

Inv:

  • raised troponin
  • ECG
    • Diffuse saddle ST-elevation
  • PR depression

Management
Viral:
limit exercise, NSAIDs, colchicine (CI in renal/ liver impairment)

Bacterial:

  • IV ABx
  • Pericardiocentesis if purulent
  • Pericardiectomy if adhesions/ recurrent tamponade
40
Q

Gold standard investigation for Infective Endocarditis

A

TransOESOPHAGEAL Echocardiogram

41
Q

Aschoff Bodies

A

Rheumatic carditis

42
Q

Typical organisms for IE

A
S viridians (poor dental)
S Bovis 
HACEK
S aureus (IV user)
Enterococcus

SSSHE