Cardiology Flashcards
Interpreting INR
Increased INR means…
INR management and blled situation:
Major bleeding (e.g. variceal haemorrhage, intracranial haemorrhage) (3)
INR > 8.0 and Minor bleeding (3 and restart when?)
Increased INR means… less likely to clot therefore bleed more
Major bleed
-Stop warfarin
- Give intravenous vitamin K 5mg
- Prothrombin complex concentrate - if not available then FFP*
Minor
- Stop warfarin
- Give intravenous vitamin K 1-3mg
- Repeat dose of vitamin K if INR still too high after 24 hours
- Restart warfarin when INR < 5.0
What is Beurgers disease? (or thromboangiitis obliterans)
Present (4)
small and medium vessel vasculitis that is strongly associated with smoking.
Young person
- smoking Hx
- extremity ischaemia ie. claudication, ischaemic ulcers
- superficial phlebitis
- Reynauds
When would you choose rate control as first-line for AF ? (3)
- whose AF has an obvious reversible cause’ (can be pneumonia)
- if there is coexistent heart failure
- First onset of AF
Management of VT- polymorphic (Tosardes de Pointes)
-If patient shows any of the 3 signs of adverse effects…
then….
If patient doesn’t show these signs
1. First-line
Other examples (3)
2.
- If patient is showing adverse signs (eg. HF, Hypotensive, Chest pain) then immediate cardioversion DC SYNCHRONISED!
- If patient is does not show these signs:
first line- Mg Sulfate
Other anti-arrythmias: - amiodarone: ideally administered through a central line
- lidocaine: use with caution in severe left ventricular impairment
- procainamide
If these fail… SYNCHRONISED DC CARDIOVERSION
First-line for acute pericarditis
a combination of NSAIDs and colchicine for patients with acute idiopathic or viral pericarditis
What would you see on an ECG if you had HYPERcalcaemia?
Shortened QT interval
Mitral Stenosis Features
- Murmur…
- Loud…
- Pulse?
- rogue (dont need explanation)
- classic
- rogue
- Mid to late-diastolic murmur heard at apex and radiates to the axilla, heard best on expiration RILE
- Loud S1 and opening snap
- Low vol pulse
- Malar flush- plum-red discolouration of the high cheeks. It is classically associated with mitral valve stenosis due to the resulting CO2 retention and its vasodilatory effects
5 Dyspnoea (increase LA pressure and inc. pul venous hypertension) - HAEMOPTYSIS (potentially pink frothy sputum)- due to pulmonary pressures and vascular congestion
How does a Hypertrophic obstructive cardiomyopathy kill young athletes?
What is assoc with the condition and can cause death but is not a complication of the condition?
ventricular tachycardia secondary to ischaemia and this typically occurs in the setting of extreme exertion.
Wolff-Parkinson White syndrome
Step-wise management of stable angina (4)
- Everyone given statin, aspirin and GTN to relieve exacerbations
- B-blocker or Rate limiting CCB
- Add the other (used in combo a long acting dihydropurine should be given ie. Amlodipine or Nifedipine (short acting Verapamil cause heart block)
- 1/4 from: Isosorbide mononitrate (long acting nitrate), ivabradind (HCN Chanel), Nicorandil (K+ channel activator), Ranolazine (anti-anginal) only whilst waiting for CABG though
Genetic pattern of familial hypercholesterolaemia
Treatment-
Autosomal dominant
high-dose statins
Which heart failure drug long term can cause pathological fracture risk and the mechanism of this
Furosamide - Hypocalcemia is a side effect of loop diuretics - most likely result in excess PTH secretion and will cause more calcium to be released from bones weakening their structure.
Coarctation of the aorta murmur?
It causes…
. Mid-systolic murmur maximal over the back is often heard
Hypertension in young person
What cardiomyopathy are alcoholics at risk of getting?
dilated cardiomyopathy
Poly cystic Kidney disease assoc with what murmur?
Mitral valve prolapse
Common Side effects of thiazide diuretics (7)
PIG and the 4 Hs
Rare Side effect (4)
PART
- Thiazides can worsen glucose tolerance- cause Hyperglycaemia
- Hypercalaemia
- Hyponatraemia
- Hypokalaemia
- p- Postural hypertension
- i - impotence
- g- gout
Rare
P- pancreatitis
a- agranulocytosis
r- rash photosensitivity
t- thrombocytopaenia