cardio/ renal drugs specific Flashcards
What is amiodrarone
(not the class)
Potassium channel blockers
Classification of amiodarone
Antiarrythmic
amiodarone MOA
prolongs repolarization by blocking potassium channels in cardiac cells
when is amidarone indicated
Indicated only for the treatment of life-threatening recurrent ventricular dysrhythmias when unresponsive to other treatments
what happens when you take amidarone
Usually hospitalized during initiation for close monitoring
Monitor BP & HR for profound hypotension and bradycardia
What should you avoid/ consider w/ AMIODARONE
Black Box warning: Fatal toxicities (pulmonary, arrhythmia exacerbation, liver, heart block)
Avoid grapefruit juice
Classification of Dilitazem
Antiarryhtmic
what does dilitazem do
Calcium channel blockers
- blocks calcium during depolarization
what might patients expieinece using dilitazem
and what should you check
Patients may experience:
Bradycardia (assess hr) – Check VItals
Edema (assess lung sounds/presence of edema)
hypotension (assess for orthostatic hypotension, advise slow positional changes)
Headache (assess bp to ensure med is working/provide analgesic)
Dizziness (D/t hypotension – Slow positional changes)
what to avoid with dilitazem
Use caution with otc/herbal medications d/t interactions
Avoid grapefruit juice
classification of adenosine
antiarryhmics
adenosine use
moa
emergent use,
slows conduction
svt–Supraventricular tachycardia
Patients may experience with adenosine
and what to check for
Prolonged asystole/absence of pulse (monitor w/ EKG)
Palpitations (monitor pulse for 1 minute)
hypotension (assess for orthostatic hypotension, monitor bp, advise slow positional changes)
Bronchospasms/shortness of breath (assess airway/lung sounds, monitor for severe sob)
Facial flushing (update PCP with presence, maintain skin integrity)
Loss of consciousness (assess loC)
Dizziness (teach on slow positional changes)
clarification of digoxin
antiarrythmics
what is digoxin
not the class
Cardiac glycosides
what does digoxin do
inhibits na/k pump to raise CO/ lower HR
Patients may experience with digoxin
Digoxin toxicity (n/v, fatigue, halos/blurring, bradycardia)
—Make sure to monitor digoxin levels (0.8-2.0 therapeutic)
Bradycardia (assess apical pulse x 1 minute – hold <60bpm)
What at risk for with digoxin
risk for toxicity d/t hypokalemia (monitor potassium level (3.5-5.0
Increased risk w/ renal impairment – can’t excrete properly so becomes toxic!!!
medication considerations with digoxin
antidote
Use extreme caution with other medications that decrease potassium (fureosemide)
Antidote: digibind
classification of nitroglycerin
vasodilator
what does nitroglycerin treat
treats angina caused by atherosclerosis (chronic pain) or MI (acute pain)
Patients may experience with nitroglycerin
Hypotension / dizziness (monitor BP after each dose, advise slow positional changes, sit down!!!)
Headache (d/t vasodilation – increased blood flow)
Sweating (may make you feel like you’re going to pass out)
n/v
what does nitroglycerin come in
comes In sl, xr tabs, creams, patches, or iv (wear gloves when applying the patch)
nitroglycerin considerations
don’t give/keep
Keep the bottle out of sunlight / away from heat (decomposes)
Do not give with sildenafil!!! (can cause severe hypotension leading to mi/cardiac death)
furosemide classifications
loop diuretic
Furosemide MOA
prevents reabsorption of na/cl in loop of kidneys
Furosemide uses to treat
Used to treat edema, heart failure & hypertension (removes fluid – potassium wasting diuretic!!!
Patients may experience with furosemide
and what to monitor
Dehydration (rehydrate w/ electrolytes)
Hypotension / dizziness (monitor BP, advise slow positional changes)
Hypokalemia (monitor kidney function, replace potassium)
Considerations with furosemide
what monitor/when take
may need to adjust dose if causing harm to kidneys
Monitor weight (3# in day / 5# in a week) – contact pcp
Do not readjust dose independently if weight gain occurs
Administer IV furosemide Slowly (can cause ototoxicity)
Take early in the morning to prevent nocturia
classification of Hydrochlorothiazide
thiazide diuretics
Hydrochlorothiazide Moa
– promotes excretion of sodium & water
Hydrochlorothiazide use
Used to manage hypertension and edema
Hydrochlorothiazide
Patients may experience:
Electrolyte depletion (rehydrate w/ electrolytes)
Hypotension / dizziness (monitor BP, slow positional changes)
Photosensitivity (use sunscreen)
Renal impairment (monitor kidney function)
Hydrochlorothiazide considerations
Thiazide diuretics are not effective for immediate diuresis
Take at the same time each day
Monitor weight
spironolactone classification
potassium sparing diuretics
spironolactone moa
promotes excretion of sodium & water but retains potassium
spironolactone use
Used to manage hypertension and edema in HF
spironolactone
Patients may experience:
Hyperkalemia (monitor kidney function, limit potassium)—Salt substitutes & Potassium rich foods (bananas, potatoes, oranges)
Hypotension / dizziness (monitor BP, advise slow positional Changes)
Dehydration (rehydrate
Spironolactone considerations
may need to adjust dose if causing harm to kidneys
Take at the same time each day