[Cardio] Atrial Fibrillation Flashcards

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1
Q

what are the causes of AF?

A
"Mrs SMITH has AF"
Sepsis
Mitral valve stenosis
Ischaemic heart disease
Thyrotoxicosis
Hypertension
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2
Q

how is a dx of AF made?

A

clinical examination (irregular pulse) + ECG (irregularly irregular, narrow complex tachycardia, absent P waves)

may need Holter monitor to dx paroxysmal AF

+ ECHO to assess for heart failure and structural heart disease in guiding long-term mx

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3
Q

what is paroxysmal AF?

A

AF that terminates <7 days of onset

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4
Q

what is persistent AF?

A

AF that fails to terminate in <7 days, episodes often require cardioversion to restore sinus rhythm

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5
Q

what is permanent AF?

A

AF that lasts >12 months and no longer pursuing rhythm control options

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6
Q

how do you manage AF?

A

depends if stable or unstable

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7
Q

how do you manage stable AF?

A

rate vs rhythm control

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8
Q

when do you use rate control in stable AF?

A

if onset >48 hours or uncertain

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9
Q

what is 1st line for rate control in stable AF?

A

beta-blockers

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10
Q

what other drugs could be used for rate control in stable AF?

A

CCBs, digoxin

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11
Q

when do you use rhythm control in stable AF?

A
  • acute onset AF <48 hours
  • heart failure caused by AF
  • pts who remain symptomatic despite rate control
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12
Q

what can be used for rhythm control in stable AF?

A
  • flecainide
  • sotalol
  • amiodarone
  • AF ablation
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13
Q

what can be considered for resistant, symptomatic AF?

A

ablation

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14
Q

unstable AF is an emergency as it causes a life-threatening haemodynamic unstability. what are the features of unstable AF?

A
  • hypotensive
  • chest pain
  • acute heart failure
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15
Q

how is unstable AF managed?

A

urgent DC cardioversion

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16
Q

all pts with AF need to be assessed for the need of long-term anticoagulation. what scoring systems are used?

A

CHADs-VASC and HASBLED

17
Q

what is CCB and Flecainide contra-indicated in?

A

structural heart disease

18
Q

what is the MOA of warfarin?

A

vit K antagonist

19
Q

what is the dosing for warfarin?

A

INR-adjusted

20
Q

what is the reversal agent for warfarin?

A

vit K PO / IV

21
Q

what is the MOA of apixaban and rivaroxaban?

A

direct FXa inhibitor

22
Q

what is the MOA of dabigatran?

A

direct thrombin inhibitor

23
Q

dabigatran is the only DOAC with a reversal agent. what is it?

A

idarucizumab

24
Q

what is the only anti-coagulant licensed for metallic valve replacement?

A

warfarin

INR 3-4