Cardio: Antihypertensive Drugs

Question 1

Describe how α-Methyldopa works and its ADRs

Answer 1

Question 2

What are the uses of Minoxidil?

Answer 2

Question 3

Describe the efficacy and PKs for Reserpine

Answer 3

Question 4

Describe the MOA and for Efficacy propranolol

Answer 4

Question 5

Describe the MOA and PK s for [Verapamil + diltiazem]

Answer 5

Question 6

Describe the general PKs of Diuretics

Answer 6

Question 7

Describe the Tolerance development seen in Hydralazine use?

Answer 7

Question 8

What are the ADRs/contraindications for Diuretics?

Answer 8

Question 9

What group of drugs does the following describe?

Answer 9

Question 10

Describe the PKs for ACE INHIBITORS

Answer 10

Question 11

List and describe the two major types of Hypertension

Answer 11

Question 12

Describe the general mechanisms of Diuretics

Answer 12

Question 13

What is the MOA and ADRs for Sodium nitroprusside?

Answer 13

Question 14

What are the two Centrally-acting sympatholytics?

Answer 14

Clonidine

α-Methyldopa

Question 15

What is the MOA for Minoxidil?

Answer 15

Question 16

Describe the PKs and ADRs for propranolol

Answer 16

Question 17

What are the Peripherally-acting sympatholytics?

Answer 17

Reserpine + the alpha-1 blockers (Prazosin, terazosin, doxazosin)

Question 18

Describe the MOA for Reserpine

Answer 18

Question 19

What is MOA for all drugs that end with -sartan?

Answer 19

Question 20

What are the ADR for Reserpine?

Answer 20

Question 21

When would you use Diuretics?

• Who do they work best on?

Answer 21

Question 22

What are the Direct-acting vasodilators?

Answer 22

Hydralazine

Minoxidil

Sodium nitroprusside

Question 23

Describe the ADRs for ACE INHIBITORS

Answer 23

Question 24

Describe the MOA and Efficacy for Clonidine

Answer 24

Question 25

What are the benefits and ADRs for [Prazosin, terazosin, doxazosin]?

Answer 25

Question 26

What does Chronic hypertension do to the baroreceptor reflex?

Answer 26

Question 27

What is Endothelin and how does it work?

Answer 27

Question 28

• What is hypertension defined as?

Answer 28

Question 29

Describe the MOA, Efficacy, and ADRs for Nifedipine

Answer 29

Question 30

Describe what EDRF is and how it works

Answer 30

Question 31

Describe the Efficacy and ADRs for [Verapamil + diltiazem]

Answer 31

Question 32

What are the three main classes of Diuretics?

Answer 32

Question 33

Describe how angiotensinogen eventually affects blood vessel size and aldosterone

Answer 33

Question 34

What are the Calcium channel antagonists?

Answer 34

[Verapamil + diltiazem] + Nifedipine (part of the Dihydropyridine class of CCB)

Question 35

What are the ADRs of Hydralazine?

Answer 35

Question 36

What are the ADRs for Angiotensin receptor blockers?

Answer 36

Question 37

What are the Lifestyle (Non-Pharmacological) Modifications for Hypertension?

Answer 37

Question 38

What is Sodium nitroprusside used for?

What does it do to afterload and preload?

Answer 38

Question 39

Describe the MOA and efficacy for [Prazosin, terazosin, doxazosin]

Answer 39