CARD 48- Pharm: Vasodilators Flashcards
1
Q
Describe the Mechanisms of Ischemia
A
2
Q
Describe the Clinical Utility of Vasodilators
A
3
Q
What is the The “Steal Phenomenon”
A
4
Q
What are the Vasodilator Mechanisms?
A
- Blockade of endogenous vasoconstrictors
- Direct relaxation of vascular smooth muscle
- Non-endothelium-dependent vasodilators
5
Q
Describe the Blockade of endogenous vasoconstrictors
A
6
Q
Describe the Direct relaxation of vascular smooth muscle
A
7
Q
Describe the Non-endothelium-dependent vasodilators
A
8
Q
Describe what Sodium Nitroprusside is used for
A
9
Q
Describe what Nitroglycerin is what its MOA
A
10
Q
Describe the PKs and ADRs of Nitroglycerin
A
11
Q
Describe Isosorbide dinitrate
A
12
Q
Describe Nifedipine
A
13
Q
Describe Dipyridamole
A
14
Q
What are the “Other Vasodilators”
A
15
Q
Describe EDRF and Endothelin
A
● Endothelin has structural similarities to venom of the Israeli burrowing asp
○ Victims die of heart attack (likely due to severe vasoconstriction)
