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Pharmacology > Cardio: Alpha/Beta Receptor Agonists > Flashcards

Cardio: Alpha/Beta Receptor Agonists Flashcards

1
Q
  • The left column is tissues and the right column is the effects of receptor activation on that tissue.
    • What receptor is associated with these tissues and effects?
A

β1

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2
Q

What is the receptor selectivity and general effects of Norepinephrine?

What is the clinical application for it?

A
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3
Q

What are the clinical applications for non-selective β agonists?

A
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4
Q

What are the general effects of α2 agonists?

A
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5
Q

What are the general clinical applications for catecholamines?

A
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6
Q

What are the general Clinical Applications for α2 Agonists?

A
  • Stimulating α2 Receptors Inhibits Sympathetic Nervous System Tone
    • Treatment of hypertension
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7
Q

What is the receptor selectivity and general effects of Dopamine?

A
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8
Q

What is ⍺-Methyldopa?

A

α2 Selective Agonist

(Prodrug, decarboxylated to a-methylnorepinephrine)

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9
Q

What are the sympathetic receptor agonist mnemonics?

A

METH and OXY increase DOPAmine, DOUBle time. Insane

  • Methoxyamine: α1 selective agonist
  • ⍺-Methyldopa: α2 selective agonist
  • Dobutamine: β1 selective agonists
  • Isoproterenol: Nonselective β agonists

AL MET SAL at the winTER FORMal

*

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10
Q

What are the general effects and clinical applications of β2 selective agonists?

A
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11
Q

What are the Receptor Selectivity and general effects of Epinephrine?

A
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12
Q

What kind of drug is Dobutamine?

A

β1 selective agonist

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13
Q

What are the β2 selective Agonist drugs?

A

AL MET SAL at the winTER FORMal

(last two last the longest [>12 hrs])

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14
Q

What kind of drug is Isoproterenol?

A

β1 and β2 agonist (non-selective β agonist)

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15
Q

Describe the catecholamine selectivity

  • Norepinephrine
  • Epinephrine
  • Dopamine
A
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16
Q

What are the general effects of ⍺-Methyldopa?

A
17
Q
  • The left column is tissues and the right column is the effects of receptor activation on that tissue.
    • What receptor is associated with these tissues and effects?
A

α1

18
Q

What are the clinical applications and ADRs for Dobutamine?

A
19
Q

What are the clinical applications and ADRs for Isoproterenol?

A
20
Q

The left column is tissues and the right column is the effects of receptor activation on that tissue.

  • What receptor is associated with these tissues and effects?
A

β2

21
Q

What are the general ADRs for Catecholamines?

A
22
Q

What is Methoxyamine used to treat and what are its ADRs?

A
23
Q

What are the effects of Isoproterenol?

A
24
Q

What are the cardiac clinical applications for dopamine?

A

Treatment of shock caused by low cardiac output and renal failure

25
Q

What are the Clinical Applications for α1 Agonists?

A
26
Q

The left column is tissues and the right column is the effects of receptor activation on that tissue.

  • What receptor is associated with these tissues and effects?
A

α2

27
Q

What kind of drug is Methoxyamine?

A

α1 Agonist

28
Q

What are the general effects of β1 agonists?

A
29
Q

What are the clinical applications and ADRs for ⍺-Methyldopa?

A
30
Q

What receptor is considered an autoreceptor?

A

α2

31
Q

What are the clinical applications for Epinephrine?

A
  • Asthma (β2)
  • Anaphylaxis (β2, β1, α1)
32
Q

What are the general clinical applications of β1 agonists?

A
  • Stimulating Sympathetic Nervous System β1 Receptors
    • Treatment of heart failure and cardiogenic shock
33
Q

What are the general effects of α1 Agonists?

A
34
Q

What are the effects of Dobutamine?

A

Pharmacology (7 decks)

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