Cardio: Alpha/Beta Receptor Antagonists

Question 1

What kind of drug is Acebutolol?

Answer 1

Selective β1 blockers, but is a PARTIAL agonist

Question 2

What are these drugs?

Question 3

What are all nonselective beta-blockers used to treat?

Answer 3

Hypertension

Question 4

What are the α1 selective blockers?

Answer 4

Pray terrible get doxxed

• Prazosin
• Terazosin
• Doxazosin

Question 5

What are the general effects of B blockers, in relation to:

• Relative receptor affinity
• Dose-dependancy
• Cardiovascular system
• Lungs
• Metabolism

Answer 5

Question 7

What are the clinical applications and ADRs of Labetalol?

Answer 7

Question 8

What are the clinical applications for β Receptors Antagonists?

(4 main ones)

Answer 8

Question 9

What are the clinical applications and ADRs of Carvedilol?

Answer 9

Question 10

What are the clinical applications and ADRs for Acebutolol?

Answer 10

Question 11

Which drug has a higher inhibitory effect on beta receptors: Labetalol or Propranolol?

Answer 11

Propranolol

Question 12

What is the β1-selective blocker that has intrinsic activity aka is a partial agonist?

Answer 12

PACE-maker

• Partial Agonist: Acebutolol

Question 13

• What is the condition is only Esmolol used to treat
  
  • (There may be other drugs but is the only selective Beta-1 blockers [FULL antagonist])
• What is unique about this drug in terms of half-life and bioavailability?

Answer 13

• Supraventricular tachycardia
• It has a half-life of 10 minutes, which is relatively much shorter than other beta blockers. It has almost 0% bioavailability.

Question 14

What condition is treated with only the non-selective beta blockers propranolol or nadolol?

Answer 14

Angina

Question 15

What are the non-selective β blockers ( β-antagonists) that do not have α1 activity?

Answer 15

• So, Tim met-a pro nas car driver for Penske
  
  • Sotalol
  • Timolol
  • Metapranolol
  • Propanolol
  • Nadolol
  • Carteolol
  • Penbutolol

Question 16

What are these drugs?

Answer 16

Nonselective beta-blockers

Question 17

What kind of drugs are Labetalol and Carvedilol?

Answer 17

Nonselective Beta Blocker Selective Alpha-1 -Blockers

Question 18

What are the general ADRs for Nonselective beta-blockers?

Answer 18

Question 19

What condition is treated with only the non-selective beta blockers propranolol or timolol?

Answer 19

Postmyocardial infarction syndrome

Question 20

What conditions are treated with only propranolol [this is the only non-selective beta blocker used for these conditions]?

Answer 20

• Heart failure
• Cardiac arrhythmia
• Idiopathic hypertrophic subaortic stenosis

Question 21

What is the clinical application of ALL Selective Beta-1 blockers [FULL antagonists)?

Answer 21

Hypertension

Question 22

• If a patient has Angina or an acute myocardial infarction, what are the two Beta-1 blockers [FULL antagonist] that you can prescribe?
  ​
  
  • What is the unique ADR that comes for using these drugs?

Answer 22

• metoprolol or atenolol
  
  • Bradyarrhythmia

Question 23

What are the general effects of α receptor antagonists?

Answer 23

Question 24

What are the β1 selective blockers?

Answer 24

The Eskimo never ate the bison because he had better meat.

• Esmolol
• Nebivolol
• Atenolol
• Bisoprolol
• Betaxolol
• Metoprolol

Question 25

What are the non-selective β blockers ( β-antagonists) that have α1 activity?

Answer 25

Caviar is made in a lab.

• Carvedilol
• Labetalol

Question 26

What are the clinical applications and ADRs of α1-receptor Antagonists?

Answer 26

Question 27

What kind of drugs are these?

Answer 27

Selective Beta-1 blockers [FULL antagonists)

Question 28

What is the ADR of ALL Selective Beta-1 blockers that are full antagonists?

Answer 28

Hypotension