Cardio Flashcards
Diamond classification
substernal or L sided chest pain
worsened w/ exertion
relieved with NTG and rest
Typical angina
3/3 of diamond classification
Atypical angina
2/3 of diamond classification
Non-anginal
0-1 of diamond classification
Diagnostic studies for angina
R/O STEMI first β 12 lead EKG
If STEMI β π¨ cath lab
If NO STEMI β troponins
If β trop β π¨cath
If no ST elev or β trop β stress testβ if β electively go to cath
Eval stress test with:
EKG β if nl baseline EKGβ β if ST Ξ
Echo β baseline EKG abnl β β if no mvt
Nuclear β prev coronary artery bypass
Clinical intervention for angina
Cath β
if β₯3 vessels β CABG
if 1-2 vessels β stent
Clin therapeutics angina
Morphine
Oβ β NC
Nitrates β if CAD + angina
*Aspirn β 1st
*Ξ²-blocker β next after aspirin
*ACE-I
*Statin
Heparin β if high sus of CAD
Clopidogrel β if stent
tPA if in rural setting and canβt get to cardiologist within 60 min
*everyone gets
What med β mortality when used to control CP
morphine
Stable Angina
Substernal chest pain w/ exertion and relieved w/ rest and NTG
β
Biomarkers
β
ST Ξ
β Stress test
Stable Angina tx
Med mgmt only
Unstable Angina
90% occlusion
demand ischemia
Chest pain at rest & nothing relieves pain
β
Biomarkers
β
ST Ξ
UA treatment
Hosp admission & cath + meds
If not treated will progress to STEMI
NSTEMI
Heart is damaged β 90% occlusion
demand ischemia
CP at rest
β troponin
β
ST elevation
NSTEMI tx
Hosp admission & cath + meds
When should you AVOID giving nitrates when a pt has chest pain
II, III, avF (inferior) ST elevations β RV infatcton β NO NITRATES bc RV is preload dependent and will cause severe hypotension
A fib mgmt
Stableβ rate control
Ξ² blockers (Metoprolol), CCB (Diltiazem, Verapamil), Digoxin preferred for rate control in pts w/ hypotension or CHF
Unstable β synchronized cardioversion
need to anticoag if >48h
Anticoagulation
NOACs β Dabigatran, Rivaroxaban, Apixaban, Edoxaban
Warfarin-Preferred if severe CKD, HIV on PI, CYP450 antiepileptics (carbamazepine, phenytoin)
INR goal of 2-3
Aspirin + Clopidogrel (not as good)
Torsades mgmt
defib + IV magnesium
V tach mgmt
If stable β Amiodarone 150 mg IV over 10 min; repeat as needed to maximum dose of 2.2 g in 24 hours
Unstable β defibrillate
If pulseless β CPR q 2 min, defib and alt epi and amio alt q 2 min
Med mgmt of sinus brady
Unstable β pace
Atropine
Mgmt of 2nd deg heart block
Atropine or temporary pacing
If you give atropine it may push into 3rd deg and worsen
Progression to 3rd deg common so pacing is definitive tx*
PEA/asystole mgmt
CPR q 2 min with epi q 4 min
NO shock
What is CHADSVASC
CHF Hypertension Age ( β₯ 65 = 1 point, β₯ 75 = 2 points) Diabetes Stroke/TIA (2 points)
VASc β peripheral arterial disease, previous MI, aortic atheroma, female gender
Duke criteria for endocarditis
pt must have 2 major OR 1 major and 3 minor OR 5 minor
Major: 2 pos blood cx, ECHO evidence of endo involv or regurg
Minor: predisposing factor, fever >100.4, vascular phenomena (embolic dz, pulm infect), immunologic phenomena (glomerulopnephirtis, osler nodes, roth spots)
Dilated Cardiomyopathy pathophys
β₯ chambers dilate β floppy + thin walls
β contractility
Dilated Cardiomyopathy sx
Sx typical of systolic CHF β orthopnea, PND, DOE, crackles, peripheral edema
Dilated Cardiomyopathy dx
Echo β dilated chambers
Dilated Cardiomyopathy tx
β EtOH, β chemo
Transplant
Goal: target CHF sx
Ξ²-blocker
ACE-I
Diuretics β furosemide
Hypertrophic Obstructive Cardiomyopathy pathophys
Unilateral septum hypertrophy β covers aortic opening β LV outlet obstruction
Hypertrophic Obstructive Cardiomyopathy sx
Young athlete*
Aortic stenosis murmur
DOE, syncope w/ exertion, sudden cardiac death
Systolic, heard best at 2nd ICS RSB (base), crescendo-decrescendo
Hypertrophic Obstructive Cardiomyopathy tx
Avoid dehydration β do not get HR up, AVOID exercise
EtOH ablation, myectomy, AICD if at β risk of death
Definitive tx β transplant
Goal: keep ventricle filled
Ξ²-blockers
CCBβ verapamil, dilatazlam
Restrictive Cardiomyopathy pathophys
Stuff gets in way of ventricle wall other than myocytes β β₯ canβt relax
Restrictive Cardiomyopathy sx
Diastolic CHF
Amyloid β peripheral neuropathy
Sarcoid β pulmonary dz
Hemochromatosis β cirrhosis or bronze diabetes
Restrictive Cardiomyopathy dx
Echo β restrictive pattern
Amyloid β fat pad or gingiva bx
Sarcoid β cardiac MRI + endomyocardial bx
Hema β screen w/ ferritin (will be β) + genetic test
Restrictive Cardiomyopathy tx
Manage underlying dz
Definitive tx = transplant
Goal: rate control + control HTN
Ξ²- blockers
CCB
Gentle diuresis
R sided HF
R sided β₯ failure β β blood to lungs β β blood to LV and β blood to periph
L sided HF
L sided β₯ failure β blood canβt get out of LV β lungs drown with fluid bc RV still works