Endocrine

Question 1

hyperca of malig tx

Answer 1

bisphosphonates if failed denosumab

IV zoledronic acid or pamidronate to prevent LT skeletal decomp

Question 2

hyperthyroid preferred agent

Answer 2

methimazole (not good for acute)

Question 3

1st line in thyroid strom

Answer 3

BB d/t dec response of cardiomyocytes to effects of TH

Question 4

PTU MOA

Answer 4

dec prod of TH and prevents conversion of T4 to T3

Question 5

MC thyroid carcinoma after radion exposure

Answer 5

papillary

Question 6

why should you avoid aspirin in pts with thyroid storm

Answer 6

inc T4 and T3

Question 7

thyroid ca with more aggressive clin course

Answer 7

follicular ca

Question 8

What meds need to be stopped to prepare for surg excision of pheochromocytoma

Answer 8

those that cause stim of pheo activity such as BB, glucagon, metoclopramise, histamine

Question 9

hypomag

Answer 9

hyporeflexia

Question 10

MC cause of hypomag

Answer 10

malnutrition

Question 11

Which hereditary syndromes are associated with pheochromocytomas?

Answer 11

von Hippel-Lindau (VHL) syndrome, multiple endocrine neoplasia type 2 (MEN 2), and neurofibromatosis type 1 (NF1)

Question 12

What is the most common cause of infectious primary adrenal insufficiency worldwide?

Answer 12

Tuberculosis

Question 13

What medication can help to reduce triglycerides by up to sixty percent?

Answer 13

Fibrates, such as fenofibrate and gemfibrozil

Question 14

Tx for prolactinoma

Answer 14

Cabergoline (dopamine agonist)

surgery if larger

Question 15

recommended treatment for a pituitary adenoma >1 cm in size

Answer 15

surgical resection

Question 16

Tx for central diabetes inspidcus

Answer 16

Desmopressin (DDAVP)

Question 17

Which of the following is a contraindication for the use of gemfibrozil in patients with hypertriglyceridemia

Answer 17

biliary dz

Question 18

What medication can be given to block enterohepatic recirculation of thyroid hormone?

Answer 18

Cholestyramine 4 gm oral every 6 hours