Cardiac syncope and sudden death

Question 1

sudden death

Answer 1

within 60 mins of symptoms

Question 2

commonest cause of syncope in hypertrophic cardiomyopathy patients

Answer 2

vasovagal syndrome

Question 3

LQTS

Answer 3

black out with exercise or startle reflex

Question 4

Brugada syndrome

Answer 4

autosomal dominant condition causing faulty sodium channels, predisposing to fatal arrhythmias, eg VF typically in young males
can be triggered by fevers
preventable by implanting a defibrillator

Question 5

catecholaminergic polymorphic VT

Answer 5

mutations in calcium channel proteins leading to excess intracellular calcium
reduces the electrical stability of the cardiomyocytes, leading to VF