Cardiac Mucle Flashcards

1
Q

Where is cardiac muscle located?

A

heart

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2
Q

What does cardiac muscle form in the heart?

A

thick layer called myocardium

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3
Q

What is the function of cardiac muscles?

A
  • pumps blood through body

- heart beat

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4
Q

What is the structure of cardiac fibers (cardiomyocytes)?

A
  • short
  • branched
  • striated
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5
Q

Are cardiac fibers (myocytes) striated?

A

yes

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6
Q

Do cardiac fibers (myocytes) have nuclei?

A

one central nucleus per fiber

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7
Q

How are cardiac fibers joined to each other?

A

joined by intercalated disks

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8
Q

Is cardiac muscle contraction voluntary or involuntary?

A

involuntary (spontaneous)

inherent rhythmicity – heart has specialized pacemaker cells that start the electrical sequence of depolarization and repolarization

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9
Q

What are intercalated disks?

A

junctional complexes found between two adjacent cardiac fibers – in a step-like pattern

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10
Q

What are the two parts of an intercalated disk?

A
transverse part (TR)
lateral part (LAT)
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11
Q

Where is the transverse part (TR) of intercalated disks?

A

runs across fibers at right angles

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12
Q

Where is the lateral part (LAT) of intercalated disks?

A

runs parallel to myofilaments

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13
Q

What are the two types of junctions in transverse part (TR) of intercalated disks?

A
  • zonula adherens

- desmosomes (macula adherens)

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14
Q

What does the zonula adherens do?

A

anchor actin myofilaments of terminal sarcomeres to plasma membrane

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15
Q

What is the one type of junction found in the lateral part (LAT) of intercalated disks?

A

gap junctions

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16
Q

What do gap junctions do?

A

ionically couples cells to allow rapid flow of information between adjacent fibers

17
Q

What is a gap junction?

A

plasma membrane of two adjacent cardiomyocytes are very close to one another

18
Q

How are T-tubules different in cardiac muscle compared to skeletal muscle?

A

wider

19
Q

Why are T-tubules wider in cardiac muscle?

A

Ca2+ must enter through T-tubule in cardiac muscle

20
Q

How is SR different in cardiac muscle compared to skeletal muscle?

A

less elaborate

  • cannot accommodate as much Ca2+
21
Q

What are the sources of Ca2+ for cardiac muscle?

A
  • SR

- extracellular milieu – flows into cell via T-tubule

22
Q

What is a diad?

A

T-tubule + one terminal cisterna

23
Q

Cardiac Muscle Contraction Process

A