Cardiac Dysfunction CHF Drugs Flashcards

1
Q

Digoxin

A
  • Cardiac Glycosides
  • inc Ca intracellularly
  • inc contractility of ventricular muscle
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2
Q

Digitoxin

A
  • Cardiac Glycosides
  • inc Ca intracellularly
  • inc contractility of ventricular muscle
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3
Q

Milrinone

A
  • Phosphodiesterase Inhibitors
  • inc cAMP in cells
  • inc heart contractility
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4
Q

Amrinone

A
  • Phosphodiesterase Inhibitors
  • inc cAMP in cells
  • inc heart contractility
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5
Q

Dobutamine

A
  • β1 agonists (Sympathomimetic)

- inc myocardial contractility

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6
Q

Atenolol

A
  • β1 antagonists
  • inc Renal H20 Excretion
  • dec renin secretion
  • dec bv –> dec edema
  • dec workload on heart
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7
Q

Metoprolol

A
  • β1 antagonists
  • inc Renal H20 Excretion
  • dec renin secretion
  • dec bv –> dec edema
  • dec workload on heart
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8
Q

Carvedilol

A
  • β1 antagonists
  • inc Renal H20 Excretion
  • dec renin secretion
  • dec bv –> dec edema
  • dec workload on heart
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9
Q

Furosemide

A
  • Loop Diuretics:
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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10
Q

Hydrochlorothiazide

A
  • Thiazides:
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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11
Q

Eplerenone

A
  • MR antagonists:
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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12
Q

Amiloride

A
  • Pore Blockers:
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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13
Q

Captopril

A
  • ACE Inhibitors:
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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14
Q

Enalapril

A
  • ACE Inhibitors:
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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15
Q

Verapamil

A
  • Vasodilators
  • Ca Channel Blockers
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
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16
Q

Diltiazem

A
  • Vasodilators
  • Ca Channel Blockers
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
17
Q

Nifedipine

A
  • Vasodilators
  • Ca Channel Blockers
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
18
Q

Amlodipine

A
  • Vasodilators
  • Ca Channel Blockers
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
19
Q

Hydrazaline

A
  • Vasodilators
  • cGMP and Ca modulator
  • inc muscle relaxation
  • blood vessel dilation
  • dec bp
  • dec work load of heart
20
Q

Isosorbide Nitrate

A
  • Vasodilators
  • Vasodilator Therapy
  • release NO, inc cGMP & dec Ca
  • relaxation of vascular smooth muscle; vasodilation
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
21
Q

Nitroprusside

A
  • Vasodilators
  • Vasodilator Therapy
  • release NO, inc cGMP & dec Ca
  • relaxation of vascular smooth muscle; vasodilation
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart