Cardiac Dysfunction CHF Flashcards
1
Q
What are the objectives for the treatment for CHF?
A
- inc myocardial contractily
- inc renal water excretion
- dec P by vasodilation
2
Q
Digoxin
Digitoxin
A
- Cardiac Glycosides
- inc Ca intracellularly
- inc contractility of ventricular muscle
3
Q
Milrinone
Amrinone
A
- Phosphodiesterase Inhibitors
- inc cAMP in cells
- inc heart contractility
4
Q
Dobutamine
A
- β1 agonists (Sympathomimetic)
- inc myocardial contractility
5
Q
Atenolol
Metoprolol
Carvedilol
A
- β1 antagonists
- inc Renal H20 Excretion
- dec renin secretion
- dec bv –> dec edema
- dec workload on heart
6
Q
Loop Diuretics: Furosemide Thiazides: Hydrochlorothiazide MR antagonists: Eplerenone Pore Blockers: Amiloride ACE Inhibitors: Captopril, Enalapril
A
- Diuretics
- inc Urine production
- dec bv
- dec edema
- dec workload on heart
7
Q
Verapamil
Diltiazem
Nifedipine
Amlodipine
A
- Vasodilators
- Ca Channel Blockers
- dec afterload
- dec TPR
- dec bp
- dec work load of heart
8
Q
Hydrazaline
A
- Vasodilators
- cGMP and Ca modulator
- inc muscle relaxation
- blood vessel dilation
- dec bp
- dec work load of heart
9
Q
Isosorbide Nitrate
Nitroprusside
A
- Vasodilators
- Vasodilator Therapy
- release NO, inc cGMP & dec Ca
- relaxation of vascular smooth muscle; vasodilation
- dec afterload
- dec TPR
- dec bp
- dec work load of heart