Cardiac Dysfunction CHF Flashcards

1
Q

What are the objectives for the treatment for CHF?

A
  • inc myocardial contractily
  • inc renal water excretion
  • dec P by vasodilation
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2
Q

Digoxin

Digitoxin

A
  • Cardiac Glycosides
  • inc Ca intracellularly
  • inc contractility of ventricular muscle
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3
Q

Milrinone

Amrinone

A
  • Phosphodiesterase Inhibitors
  • inc cAMP in cells
  • inc heart contractility
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4
Q

Dobutamine

A
  • β1 agonists (Sympathomimetic)

- inc myocardial contractility

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5
Q

Atenolol
Metoprolol
Carvedilol

A
  • β1 antagonists
  • inc Renal H20 Excretion
  • dec renin secretion
  • dec bv –> dec edema
  • dec workload on heart
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6
Q
Loop Diuretics: Furosemide
Thiazides: Hydrochlorothiazide
MR antagonists: Eplerenone
Pore Blockers: Amiloride
ACE Inhibitors: Captopril, Enalapril
A
  • Diuretics
  • inc Urine production
  • dec bv
  • dec edema
  • dec workload on heart
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7
Q

Verapamil
Diltiazem
Nifedipine
Amlodipine

A
  • Vasodilators
  • Ca Channel Blockers
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
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8
Q

Hydrazaline

A
  • Vasodilators
  • cGMP and Ca modulator
  • inc muscle relaxation
  • blood vessel dilation
  • dec bp
  • dec work load of heart
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9
Q

Isosorbide Nitrate

Nitroprusside

A
  • Vasodilators
  • Vasodilator Therapy
  • release NO, inc cGMP & dec Ca
  • relaxation of vascular smooth muscle; vasodilation
  • dec afterload
  • dec TPR
  • dec bp
  • dec work load of heart
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