card review II Flashcards
what antibody is associated with primary sclerosing colangitis
P-ANCA
Are exudative plural effusions acidic, basic or normal
acidic
what are the features of Zollinger-Ellison syndrome
multiple, refractory peptic ulcers, with ulcers that are distal to the duodenum, chronic diarrhea.
there is elevated serum gastrin, (>1000) in the presence of normal gastric pH (<4)
what is the work up for ZE syndrome
endoscopy, CT/MRI and somatostatin receptor scintigraphy for tumor localization
what genetic condition is associated with ZE
MEN1
what is the definition of acute liver failure e
NO underlying disease, severe liver injury (AST/ALT > 1000), with hepatic encephalopathy and impaired synthetic function (INR > 1.5)
what are the features of Crohn’s disease
skip lesions, extending from mouth to the anus, rectum spared, perianal abscesses, non caveating granuloma, transmural inflammation, linear mucosal ulcerations, cobblestoning, creeping fat, diarrhea, fistulas, strictures
what are the features of ulcerative colitis
rectum (always) and colon, continuous lessons, no granuloma, mucosal and submucosal inflammation, pseudo polyps, bloody diarrhea, toxic megacolon
what are the features of primary sclerosing colangitis
fatigue and pruritis, 90% have underlying inflmmatory bowel disease, cholestatic liver function panels (aminotransferase <300) multifocal stricturing dilation of the intrahepatic and or extra hepatic bile ducts, fibrous obliteration of the bile ducts with concentric replacement by connective tissue in an onion skin pattern.
what is used to stabilize cardiac membrane in hyperkalemia
calcium infusion. Calcium glutinate.
what drug is infamous for turning your urine red
rifampin
what is hepatic hydrothroax
possible complication of cirrhosis that causes transudative plural effusions due to defects in the diaphragm, especially on the right.
so in patients with liver failure, listen to their lungs because of hepatic hydrothorax, especially on the right.
what does a mitral valve regurgitation sound like
holosystolic, blowing murmur, loudest at the apex of the heart and radiates to the axilla, enhanced by maneuvers that increase the total peripheral resistance, such as squatting
what are the causes of mitral valve regurgitation
ischemic heart disease, LV dilation, MVP
what is a tricuspid valve regurgitation
holosystolic, blowing murmur, loudest at thetricuspid area and radiates to the right sternal border. enhanced by inspiration or things that increase venous return. commonly caused by right ventricular dilation. rheumatic fever and infective endocarditis can cause either MR TR
what is an aortic stenosis murmur
crescendo-decrescendo, systolic ejection murmur, LV»aortic pressure during stole
loudest at the base and radiates to the carotids, Pulsus Parus et tardus –pulses are weak with a delayed peak. Can lead to syncope angina, and dyspnea on exertion,
what is often the cause of aortic stenosis
age related calcifications. or a bicuspid valve.
what drug delays the progression of primary billiary cholangitis
ursodeoxycholic acid
what is primary billiary colangitis
autoimmune destruction of the intrahepatic bile ducts. typically affects middle aged women, with an insidious onset of fatigue and pruritis, progressive jaundice, hepatomegaly, cirrhosis, cutaneous xanthomas.
what antibody is associated with primary biliary colangitis
antimitochondrial
what are the labs for primary biliary cholangitis
> > alkaline phos, increased transferases.
severe hypercholesteremia
what are the complications of primary biliary cholangitis
malabsorption, fat-solulable vit deficiency hepatocellular carcinoma, metabolic bone disease.
what is seen in post-streptococcal glomerulonephritis
usually 10-21 after URI, more common in children, (6-10), gross hematuria, low complement C3 levels, elevated streptolysin O and anti-DNAse B, RBC casts, mild proteinuria
what is the pharmaceutical therapy to reduce overall CVD mortality in peripheral artery disease
anti platelet (aspirin) and a statin
statins stabilize atherosclerotic plaques
who gets focal segmental glomerulonephritis
fat, black, heroin, HIV
what are the labs for acute tubular necrosis
elevated BUN and creatinine (<20:1 ratio) urine sodium >20 and FeNA >2% kidneys are not working and cannot reabsorb.
What effect does alcohol have on the CVS
causes hypertension
is aspirin an anti platelet
yes
what is tamsulosin
alpha 1 blocker
what is the definition of nephrotic syndrome
edema, hypoalbuminemia, and proteinuria >3.5g/24 hours
what are the causes of WBC casts
acute interstitial nephritis, pyenephritis
what does elevated PCWP indicate
cardiogenic origin; typically cardiogenic shock
what is the CHADSVAS scoring
Congestive heart failure Hypertension Age2 ≥75 Diabetes mellitus Stroke2/TIA/thromboembolus Vascular disease Age 65-74 Sex category (female)
If there is a 2, then its worth two points. maximum score of 9.
0 score, low risk, no treatment.
1 intermediate, aspirin or oral coagulant
2 or higher, High, oral anticoagulants
what antihypertensive is associated with peripheral edema
dihydropyridine calcium channel blockers
what is a cause of dilated cardiomyopathy and how does it present
coxsackie virus B.
recent URI then CHF, dilated ventricles, with diffuse hypokinesia, and low ejection fraction.
what is the initial management of a patient with pulmonary HTN that presents with JVD, low ejection fraction, bibasilar crackles,
loop diuretics and ACEi
the loop will help with the fluid overload and the ACE will stop further cardiac remodeling
If you have a patient in renal failure what should you think
uremia
If you have renal failure patient with pericarditis, what should you think
uremic pericarditis
what is the treatment for uremic pericarditis
hemodialysis NSAIDs
what is the first test for acute pancreatitis
amylase and lipase
what is the treatment for a hemodynamically stable patient with beta blocker over dosse
atropine and IV fluids
what is the treatment for a refractory beta blocker overdose patient
glucagon
why are beta blockers and CCB used for chronic stable angina
they are first line therapies because they reduce cardiac contractility and heart rate.
what is the work up for a patient with chest pain but a low risk for CAD
No further work up
what is the most common cause of sudden cardiac arrest in the immediate post infarction period
reentrant ventricular arrhythmia
what two antibodies are associated with celiac
IgA antiendomysial and antitissue transglutaminase
what is the most effective non pharmacological way to reduce BP in an otherwise healthy smoker with alcohol history
DASH dietary approaches to stopping hypertension
what is the presentation of acute bronchitis
preceding respiratory illness, cough for 5 days to 3 weeks, can be productive, absent systemic findings, wheezing or rhonchi, chest wall tenderness.
how does ventricular aneurysm pressent
2 months post MI CHF with persistent elevations/deep Q waves on ECG
what do you always give with IV acyclovir
IV fluids because it reduces the strain on the kidneys
when you see atherosclerosis what should you think
hypertension
what acid-base disturbance is associated with addisons and why
normal anion-gap metabolic acidosis
decreased aldoteromne means less Na in less acid and potassium out
what is the S4 and what is it associated with
atrial gallop. myocardial infarction
when is the S4 sound normal
in OLDER adults
when is the S4 abnormal
in younger adults and children. indicates ventricular hypertrophy and acute MI
what is the cause of a unilateral varicocele that fails to empty when the patient is laying down
renal cell carcinoma
what are the associated findings indicative of renal cell carcinoma
fever, anemia/erythrocytosis, thrombocytosis hypercalcemia, cachexia
what is SIADH
syndrome of inappropriate antidiuretic hormone causes the body to retain too much water.
what is nephrogenic diabetes insipidus
This is when the kidney cannot concentrate urine, thus the body excretes excessive dilute urine. It is not responsive to Desmopressin or water deprivation.
what imaging test is preferred for acalculus cholecystitis
ultrasound
what happens when people have multiple blood transfusions
they become hypocalcemia because of the citrate.
what is trousseau sign for hypocalcemia
you place a cuff around the persons arm and inflate it higher than the systolic bp and then the hand flexes
what is the first line therapy for central diabetes insidious
desmopressin
what is the treatment for hypocalcemia
calcium gluconate
what does aldosterone do
when secreted in the body it’s job is to retain fluid, the RAAS system. this system retains sodium and excretes potassium