Carcinogens Flashcards
Aflatoxins (aspergillus)
Organ: liver
Impact: hepatocellular carcinoma
Alkylating agents
Organ: blood
Impact: leukemia/lymphoma
Aromatic amines (benzime, 2-naphthylamine)
Organ: bladder
Impact: transitional cell carcinoma
Arsenic
Liver - angiosarcoma
Lung - lung cancer
Skin - squamous cell carcinoma
Asbestos
Organ: lung
Impact: bronchogenic carcinoma > mesothelioma
Carbon tetrachloride
Organ: liver
Impact: centrilobular necrosis, fatty change
Cigarette smoke
Bladder - transitional cell carcinoma Cervix - cervical carcinoma Esophagus - squamous cell carcinoma/ adenocarcinoma Kidney - renal cell carcinoma Larynx - squamous cell carcinoma Lung - squamous and small cell carcinoma Pancreas - pancreatic adenocarcinoma
Ethanol
Esophagus - squamous cell carcinoma
Liver - hepatocellular carcinoma
Ionizing radiation
Organ: thyroid
Impact: papillary thyroid carcinoma
Nitrosamines (smoked foods)
Organ: stomach
Impact: gastric cancer
Radon
Organ: lung
Impact: lung cancer (2nd leading cause after cigarette smoke)
Vinyl chloride
Organ: liver
Impact: angiosarcoma