Carbohydrates, Lipids, Proteins Flashcards
Isomers
Compounds that have the same chemical formula but different structures
Epimers
Carbohydrate isomers that differ in configuration around only one specific carbon atom
Enantiomers
Pairs of structures that are mirror images of eachother
Glyceraldehyde
D and L designations are based on the configuration of the single asymmetric carbon atom in this
Most naturally occurring sugars are
D isomers (right OH)
Glucose
Primary enregy source, preferred for brain, required of cells with few/no mitochondria
essential in exercising muscle
source: diet, degradation of glygogen, gluconeogenesis
Fructose
sweeter than glucose
source: fruits, vegetables, honey
Galactose
less sweet than glucose
Source: dairy products
Sucrose
Glucose + fructose
sugar cane and beets
Maltose
Glucose + glucose
Major degradation product of starch, malt sugar
Lactose
Galactose + glucose
mammalian milk, milk sugar
Cellulose
structural polysaccharide (maj constituent of plant cell walls)
starch
storage polysaccharide (prevalent in all plant seeds and tubers)
glycogen
storage polysachharide
branched polymer
Types of starch
Amylopectin/amylose
digestion of carbs
mouth - salivary a-amylase
small intestine - pancreatic a-amylase
upper jejunum - dextrinase and glucoamylase cleave oligosaccharides, isomaltase, maltase, sucrase, lactase
glucose and galactose absorbed by
sodium-dependent glucose cotransporter 1 (SGLT-1)
fructose absorbed by
sodium-independent monosaccharide transporter (GLUT-5)
5 Classes of Lipids
- Fatty Acids
- Triacylglycerols (fats and oils)
- Glycerolphospholipids (membrane lipids)
- Sphingolipids (membrane lipids)
- Cholesterol
Functions of lipids
- Membrane structure in cells and organelles
- Major source of energy
- Cell signalling (steroid hormones and prostaglandins)
- Fat pads around organs and joints
- Provide electrical insulation for myelinated nerves
Triacylglycerol
- Simplest form
- Formed from fatty acids and glycerol
- Each triglyceride has 3 ester linkages formed by dehydration reactions between the COOH group of fatty acid and each OH group of the glycerol
- Body’s MAIN source of energy, stored in adipose
Non-esterified fats
are free fatty acids which are the major fuel for metabolism
Essential fatty acids
Can’t be synthesized by the body, must be acquired from food
Membrane lipids are made of
- Phospholipids
- Glycolipids
- Cholesterol - precursor for other substances e.g bile salts, steroid hormone, vitamin D
When lipids enter the duodenum..
- The gall bladder secretes bile salts to emulsify the fats before digestion –> small globules.
- Triglycerides are then digested by lipase from the pancreas –> free fatty acids
How are free fatty acids absorbed?
Transported to intestinal microvilli on enterocytes for absorption. Small-chain fatty acids can diffuse directly into the bloodstream
After larger triglycerides are absorbed
They are reassembled in the SER and packaged with cholesterol into chylomicrons
What are chylomicrons?
The largest and least dense lipoproteins which enter the lymphatic system and are deposited into the venous circulation via the thoracic duct.