Antibiotics

Question 1

Beta-lactams

Answer 1

Stops petidoglycan wall and cross-linking
Bactericidal
Penicillin, flucloxacillin, amoxicillin

Question 2

Examples of Beta lactams

Answer 2

Penicillin, flucloxacillin, amoxicillin

Question 3

Macrolides

Answer 3

Inhibition of protein synthesis by binding to bacterial ribosomes
Bacteriostatic AND cidal
Erythromycin, Clarithromycin

Question 4

Examples of Macrolides

Answer 4

Erythromycin, clarithromycin

Question 5

Aminoglycosides

Answer 5

Create fissure in cell membrane causing leakage

Bactericidal

Question 6

Examples of Aminoglyosides

Answer 6

Gentamicin, streptomycin

Question 7

Quinolones

Answer 7

Inhibit DNA replication by binding to topoisomerases

Bactericidal, broad spectrum

Question 8

Glycopeptides

Answer 8

Inhibit cell wall synthesis by binding to free carboxyl end
Bactericidal, gram+ve
vancomycin

Question 9

Example of a Glycopeptide

Answer 9

Vancomycin

Question 10

Name an example of broad spectrum antibiotic

Answer 10

Penicillin

Quinolones

Question 11

Name the only class which is bacteriostatic and bactericidal

Answer 11

Macrolides

Question 12

Example of a quinolone

Answer 12

Ciprofloxacin

Question 13

Sulphonamides

Answer 13

Interfere with folate synthesis

Bacteriostatic

Question 14

Example of a sulphonamide

Answer 14

Trimethoprim

Question 15

Which is the only bacteriostatic class

Answer 15

Sulphonamides