CARBOHYDRATES Flashcards
Most abundant organic molecules in nature.
CARBOHYDRATES
First product formed in photosynthesis.
CARBOHYDRATES
Are aldehyde or ketone alcohols containing carbon, hydrogen and oxygen in which the hydrogen and oxygen are generally in the same ratio as in water.
CARBOHYDRATES
Emperical formula for simpler carbohydrates _______ hence the name ______.
(CH2O)N
HYDRATE OF CARBON
Storage form of energy in the body.
CARBOHYDRATES
Serves as structural component of many
organisms.
CARBOHYDRATES
Ingredient in food and beverage industries.
CARBOHYDRATES
Excipients in pharmaceutical formulations.
CARBOHYDRATES
Pharmacologic effect.
CARBOHYDRATES
compounds that cannot be hydrolyzed to simple sugars.
SACCHARIDES (SUGAR)
5 classifications of saccharides
MONOSACCHARIDES
DISACCHARIDES
TRISACCHARIDES
TETRASACCHARIDES
OLIGOSACCHARIDES
are polymers of monosaccharides.
POLYSACCHARIDES
Starch, Inulin, Cellulose
POLYSACCHARIDES
Chemically defined as substances belonging to the carbohydrates group that is ketonic or aldehydic substitution product of a polyhydroxy alcohol.
MONOSACCHARIDES
These sugars contain from 3 to 9 carbon atoms, but those with 5 and 6 carbon atoms ( Pentoses C5H10O5, Hexoses C6H12O6)
MONOSACCHARIDES
simplest does not occur free in nature.
DIOSES (HYDROXYACETALDEHYDE)
usually in the form of phosphate esters.
TRIOSES (GLYCERALDEHYDE AND DIHYDROXYACETONE)
not found in the free state.
TETROSES
occur commonly in nature, usually as products of hydrolysis of hemicellulose, gums and mucilages.
PENTOSES
most important monosaccharides found in plants, first detectable sugars synthesized by plants and forms units from which most polysaccharides are constructed.
HEXOSES
___ possible aldohexose,__ ketohexoses
__ isomers (alpha and beta forms)
__occur in the free state:
16,8
48
2
found in sweet fruits, honey, and invert sugar.
D-fructose (Levulose) and D-glucose (Dextrose)
important in the glucose metabolism of animals and in the photosynthesis processes of plants
HEPTOSES
- Trioses – __ Carbon atoms (_______)
- Tetroses– __ Carbon atoms ( ______)
- Pentoses– ___ Carbon atoms (_______)
- Hexoses – __ Carbon atoms (_______)
- Heptoses– __ Carbon atoms (_________)
- Nonoses– __ Carbon atoms (________)
3, GLYCERALDEHYDE
4, ERYTHROSE
5, RIBOSE
6, GLUCOSE
7, SEDOHEPTULOSE
8, NURAMINIC ACID
Only disaccharide that occurs
abundantly in free state in plants (fruit juices, sugar cane, sugar beet and sap of certain maples). It yield sugar– with epimolecular quantities of glucose and
fructose
SUCROSE
seldom occur in free state. Produced in
large quantities by hydrolysis of starch during the germination of barley and other grains.
MALTOSE
milk sugar, hydrolyzed into glucose and
galactose.
LACTOSE
7 Pharmaceutically Important Sugars
Sucrose
Glucose/Dextrose
Fructose
Lactose
Xylose
Caramel (Burnt Sugar Coloring)
Honey
SUCROSE:
Common Name
Source
Scientific Name
Uses:
SUGAR, SACCHARUM
SUGAR CANE
SACCHARUM OFFICINARUM/ BETA VULGARIS
PHARMACETUCALLY NECESSITY FOR SYRUPS, DEMULCENT, NUTRIENTS
•Crushing between iron rollers
• Boiled with lime to neutralize plant acids.
• Albumins will rise on top and removed.
• Filtered and decolorized with sulfur dioxide.
• Concentrate and crystallized.
SUGAR CANE
• Beets are dug and washed.
• Sliced into small, limp silvers known as cosettes
• Sucrose is extracted with hot water.
SUGAR BEETS
D-glucose?
DEXTROSE
Is usually obtained by the hydrolysis of starch
DEXTROSE
DEXTROSE:
Source
Scientific Name
Family
Uses:
Grapes and Other Fruits
Vitis Vinifera
Vitaceae
Nutrient, ingredient in various preparations
•Dextrose injection
•Alcohol and Dextrose injection
•Dextrose and NaCl injection
crystalline dextrose
monohydrate that has undergone less rigorous purification.
Use: Pharmaceutic necessity
DEXTROSE EXCIPIENT
purified mixture of saccharides (not less
than 93% dextrose) prepared by controlled enzymatic hydrolysis of starch.
Use: Pharmaceutic necessity
DEXTRATES
product of incomplete hydrolysis of starch.
LIQUID GLUCOSE
Colorless or yellowish, thick syrup liquid that is nearly odorless and taste sweet.
LIQUID GLUCOSE
Uses: Manufacture of candy, carbonated
beverages, ice cream, baking products and in canning industry.
LIQUID GLUCOSE
Fruit Sugar
FRUCTOSE
Obtained by the inversion of aqueous solutions of sucrose and the
subsequent separation of fructose from glucose.
FRUCTOSE
Occurs most in sweet fruits and in honey.
Colorless crystals or as white crystalline or granular.
Odorless powder that has a sweet taste.
Freely soluble in water.
FRUCTOSE
Uses:
• As food for diabetic patient.
• Contained in infant feeding formulas.
• Ingredient of fructose injection and fructose, and sodium chloride injection.
FRUCTOSE
Milk Sugar
LACTOSE
Crystallized from Whey
LACTOSE
Impure crystals are redissolved in water, decolorized with charcoal, and recrystallized.
LACTOSE
Uses:
• Tablet diluents
• Nutrient in infant’s food
• Establishes intestinal microflora
LACTOSE
Semi-synthetic sugar prepared by alkaline
rearrangement of lactose.
•Yields lactose and galactose upon hydrolysis.
Use: Laxative
LACTULOSE
White, opaque liquid that is an emulsion of minute fat globules suspended in a solution of casein, albumin, lactose and inorganic salts.
COW’S MILK
6 Milk/Dairy Products
BUTTER
BUTTER MILK
SKIMMED BUTTER
COAGULUM
CHEESE
WHEY
Formed when fat globules in milk unite.
BUTTER
Liquid left after fat globules unite.
BUTTER MILK
Milk left after separation of cream.
SKIMMED MILK
Formed when skimmed milk is treated
with renin.
COAGULUM
Formed when skimmed milk is treated
with renin.
COAGULUM
Produced when coagulum is treated
CHEESE
Liquid separated from the coagulum.
WHEY
Wood Sugar
XYLOSE
A pentose obtained by boiling corn cobs, straw or similar materials with dilute acid to hydrolyze the xylan polymer.
XYLOSE
Uses:
•Diagnostic agent to evaluate intestinal absorption.
•Cellac agent
•Crohn’s disease
•Pellagra
•Radiation enteritis and surgical resection
XYLOSE
Are polymers of monosaccharides linked together through glycosidic linkages.
POLYSACCHARIDES
Glycan
Nomenclature: Nature of monosaccharide building units and the position and configuration of the glycosidic bonds.
POLYSACCHARIDES
CLASSIFICATION OF POLYSACCHARIDES
Complex Polysaccharides
Homoglycans
Gums and Mucilages
Algal Gelling Agents
Usually hydrolyzed to a component Hexose and are therefore called Hexosans,
COMPLEX POLYSACCHARIDE
which yields glucose (glycosan/glucan)
STARCH
which yields fructose (fructosan/fructan)
INULIN
forms the primary cell wall in plants
CELLULOSE
high molecular weight
polysaccharides but are considerably more soluble and more easily hydrolyzed.
HEMICELLULOSES
Starch
Hetastarch
Dextran
Inulin
Cellulose
Powdered Cellulose
Purified Cotton
COMPLEX POLYSSACHARIDES
Starch
Hetastarch
Dextran
Inulin
Cellulose
Powdered Cellulose
Purified Cotton
COMPLEX POLYSSACHARIDES
Natural plant hydrocolloids that may be classified as anionic or nonionic polysaccharides or salts of polysaccharides.
GUMS AND MUCILAGES
Dispersion of gum in water.
MUCILAGES
Uses:
Pharmaceutical necessity.
Ingredients in dental and other adhesives and bulk laxatives.
GUMS AND MUCILAGES
Tragacanth
Agar
Carrageenan
Acacia gum
Ghatti Gum
Guar Gum
Karaya Gum (Sterculia Gum)
Xanthan Gum
Locust Bean Gum
Psyllium (Flea seed)
Plantago Seed
Marshmallow leaf
Marshmallow root
Mullien flower
Couch grass rhizome
Na Alginate (Algin)
GUMS AND MUCILAGES
Agar
Alginic Acid
ALGAL GELLING AGENTS
Honey
Figs
Fucus
Cetraria– Iceland moss
MISCELLANEOUS
General term for group of polysaccharides present in the primary cell wall of all seed-bearing plants acts as an intercellular cementing material together with
cellulose and hemicellulose.
PECTIN
limp silver known as _____
cosettes
Usually hydrolyzed to a component hexose and are therefore called _____
Hexosans
CLASSIFICATION OF POLYSACCHARIDES
COMPLEX POLYSACCHARIDE
HEMOGLYCANS
ALGAL GELLING AGENTS
GUMA AND MUCILAGES
COMPLEX POLYSSACHARIDES
STARCH
HETASTARCH
DEXTRAN
INULIN
CELLULOSE
POWDERED CELLULOSE
PURIFIED COTTON
Exudates gums, seed gums, marine gums, microbial gums
GUMS AND MUCILAGES
pure pectin
PHARMACEUTIC PECTIN
Contains sugar of organic acids
COMMERCIAL PECTIN